Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.62 |
| ▸ | MGLL | Q99685 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | CCR8 | P51685 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100678 | 0.87 | ALDH1A1 (0.73) | FAAHMGLLALDH1A1USP2GAA | |
| SCHEMBL6529044 | 0.80 | OPRM1 (0.50) | FAAHMGLLALDH1A1GAACCR8 | |
| SCHEMBL6528291 | 0.80 | LMNA (0.56) | FAAHMGLLALDH1A1CCR8KDM4E | |
| SCHEMBL15243730 | 0.76 | MBTD1 (0.62) | ALDH1A1GAACCR8KDM4EHTT | |
| SCHEMBL6496007 | 0.76 | OPRM1 (0.83) | DRD2DRD4OPRM1 | |
| SCHEMBL6501384 | 0.76 | ALDH1A1 (0.66) | FAAHALDH1A1GAACCR8KDM4E | |
| SCHEMBL6528091 | 0.75 | OPRM1 (0.66) | ALDH1A1CCR8KDM4EHTTTDP1 | |
| SCHEMBL6528757 | 0.74 | KDM4E (0.64) | ALDH1A1GAACCR8KDM4EHTT | |
| SCHEMBL27589107 | 0.74 | USP2 (0.65) | ALDH1A1USP2GAACHRM4NPSR1 | |
| SCHEMBL17538382 | 0.74 | CYP3A4 (0.58) | ALDH1A1USP2GAACHRM4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003037271-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREFOR | MILLENNIUM PHARMACEUTICALS,INC. (US) | 2003-05-08 | — | — | WO | disclosed |