SCHEMBL7174236

SCHEMBL7174236

COC(=O)c1cccc(OC)c1-c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 2/20 0.62
FABP3 P05413 1/20 0.62
FABP5 Q01469 1/20 0.62
FGFR1 P11362 1/20 0.56
SRC P12931 1/20 0.56
FGFR2 P21802 1/20 0.56
FGFR4 P22455 1/20 0.56
FGFR3 P22607 1/20 0.56
SLC6A3 Q01959 2/20 0.53
TSHR P16473 3/20 0.53
MAPT P10636 3/20 0.53
GAA P10253 3/20 0.53
HSD17B10 Q99714 2/20 0.53
MAPK1 P28482 1/20 0.53
KMT2A Q03164 3/20 0.51
HTT P42858 3/20 0.51
MEN1 O00255 2/20 0.51
MAPK10 P53779 1/20 0.51
PTK2B Q14289 1/20 0.51
NCOA1 Q15788 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18315876 0.88 TSHR (0.56) FABP4FABP3FABP5FGFR1SRC
SCHEMBL27512908 0.87 FABP4 (0.56) FABP4FABP3FABP5FGFR1SRC
SCHEMBL1638898 0.87 SLC6A3 (0.54) FABP4FABP3FABP5FGFR1SRC
SCHEMBL5845535 0.86 FABP4 (0.70) FABP4FABP3FABP5FGFR1SRC
SCHEMBL7107138 0.84 TSHR (0.57) FABP4FABP3FABP5TSHRMAPT
SCHEMBL7481393 0.83 TSHR (0.63) FABP4FABP3FABP5FGFR1SRC
SCHEMBL2362774 0.83 FABP3 (0.58) FABP4FABP3FABP5FGFR1SRC
SCHEMBL7430974 0.83 FABP4 (0.58) FABP4FABP3FABP5FGFR1SRC
SCHEMBL13495445 0.83 MAPT (0.55) FABP4FABP3FABP5FGFR1SRC
SCHEMBL6697433 0.83 HPGD (0.55) FABP4FABP3FABP5FGFR1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003068736-A2 MIXED STEROIDAL 1,2,4,5-TETRAOXANE COMPOUNDS AND METHODS OF MAKING AND USING THEREOF U.S. ARMY MEDICAL RESEARCH AND MATERIAL COMMAND (US) 2003-08-21 WO disclosed
US-6558712-B1 Stable, water soluble purified shilajit extract containing sponge like fulvic acid carrier punctured by voids filled by active ingredient NATREON INC. 2003-05-06 US disclosed