Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.33 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719269 | 0.85 | ALDH1A1 (0.43) | MTNR1AMTNR1BALDH1A1DRD2DRD4 | |
| SCHEMBL294482 | 0.82 | ALDH1A1 (0.42) | MTNR1AMTNR1BALDH1A1DRD2DRD4 | |
| SCHEMBL720974 | 0.78 | POLB (0.39) | MTNR1AMTNR1BALDH1A1KDM4EPOLB | |
| SCHEMBL285271 | 0.76 | TDP1 (0.39) | MTNR1AMTNR1BALDH1A1KDM4ERAB9A | |
| SCHEMBL719664 | 0.74 | NPC1 (0.48) | MTNR1AMTNR1BALDH1A1KDM4ENPC1 | |
| SCHEMBL716724 | 0.74 | NPC1 (0.48) | MTNR1AMTNR1BALDH1A1KDM4ENPC1 | |
| SCHEMBL285278 | 0.72 | POLB (0.40) | MTNR1AMTNR1BALDH1A1KDM4ENPC1 | |
| SCHEMBL718250 | 0.71 | POLB (0.40) | MTNR1AMTNR1BALDH1A1KDM4ENPC1 | |
| SCHEMBL720076 | 0.70 | NPC1 (0.41) | MTNR1AMTNR1BALDH1A1DRD2DRD4 | |
| SCHEMBL299746 | 0.69 | NPC1 (0.43) | MTNR1AMTNR1BALDH1A1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729203-B2 | Polymer composition | CONTAMAC LIMITED (GB) | 2014-05-20 | — | — | US | disclosed |
| US-20120053313-A1 | POLYMER COMPOSITION | CONTAMAC LIMITED (GB) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053313-A1 | POLYMER COMPOSITION | UACA, CRYAA, CRYZ | MTNR1A 4207/4885MTNR1B 3998/4885ALDH1A1 3560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.