Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 7/20 | 0.35 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.34 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.34 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6493836 | 0.88 | PTGS2 (0.38) | PTGS2PTGS1RORCALKBH2ALKBH5 | |
| SCHEMBL7170792 | 0.81 | RORC (0.42) | RORCALKBH2ALKBH3FTOFLT1 | |
| SCHEMBL6501193 | 0.79 | ALDH1A1 (0.40) | PTGS2PTGS1ALKBH2ALKBH5ALKBH3 | |
| SCHEMBL6492195 | 0.78 | PTGS2 (0.38) | PTGS2PTGS1RORCALKBH2ALKBH5 | |
| SCHEMBL7065650 | 0.78 | ALDH1A1 (0.39) | PTGS2PTGS1ALKBH2ALKBH5ALKBH3 | |
| SCHEMBL6492586 | 0.74 | PPARG (0.44) | RORC | |
| SCHEMBL6498241 | 0.73 | SCN9A (0.33) | RORCEGFR | |
| SCHEMBL6498248 | 0.73 | SCN9A (0.33) | RORCEGFR | |
| SCHEMBL6490770 | 0.72 | P2RX3 (0.39) | KMT2A | |
| SCHEMBL6490070 | 0.72 | PTGS2 (0.44) | PTGS2PTGS1ALKBH2ALKBH5ALKBH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6573274-B1 | Treatment of the diseases curable based on a hypoglycemic action, and the diseases curable based on a cGMP-PDE inhibitory action, a smooth muscle relaxing action, a bronchodilating action, a vasodilating action, a smooth muscle | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2003-06-03 | — | — | US | claimed |