Toluene

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Toluene SCHEMBL717526	1.00	TSHR (0.48)	TSHRALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL11795376	0.83	KMT2A (0.47)	TSHRALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL10877958	0.83	MAPT (0.50)	TSHRALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL4398048	0.83	ALDH1A1 (0.47)	TSHRALDH1A1SMN1; SMN2MEN1KMT2A
	Toluene SCHEMBL26121009	0.83	TSHR (0.44)	TSHRALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL11795381	0.83	KMT2A (0.47)	TSHRALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL10877963	0.83	MAPT (0.50)	TSHRALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL15843753	0.83	ALDH1A1 (0.56)	TSHRALDH1A1KMT2AGAAPOLB
	SCHEMBL15843754	0.83	ALDH1A1 (0.56)	TSHRALDH1A1KMT2AGAAPOLB
	SCHEMBL263877	0.83	ALDH1A1 (0.47)	TSHRALDH1A1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.