Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL717547 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1FAAHTRPV1PPARA | |
| SCHEMBL5406268 | 0.85 | FAAH (0.48) | KDM4EALDH1A1FAAHTRPV1PPARA | |
| SCHEMBL5406278 | 0.85 | FAAH (0.48) | KDM4EALDH1A1FAAHTRPV1PPARA | |
| SCHEMBL716853 | 0.83 | SLC6A5 (0.38) | FAAHTRPV1PPARACNR2 | |
| SCHEMBL716855 | 0.83 | SLC6A5 (0.38) | FAAHTRPV1PPARACNR2 | |
| SCHEMBL717827 | 0.81 | FFAR1 (0.33) | FAAHTRPV1CNR2 | |
| SCHEMBL717828 | 0.81 | FFAR1 (0.33) | FAAHTRPV1CNR2 | |
| SCHEMBL27381276 | 0.80 | FFAR1 (0.47) | KDM4EALDH1A1FAAHTRPV1PPARA | |
| SCHEMBL12664505 | 0.80 | ALDH1A1 (0.51) | KDM4EALDH1A1FAAHTRPV1 | |
| SCHEMBL15397465 | 0.80 | ALDH1A1 (0.51) | KDM4EALDH1A1FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604255-B1 | Novel reagents for transfection of eukaryotic cells | MOLECULAR TRANSFER INC (US) | 2017-10-25 | — | — | EP | disclosed |
| US-8759499-B2 | Lipids for transfection of Eukaryotic cells | MOLECULAR TRANSFER, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| EP-2604255-A1 | Novel reagents for transfection of eukaryotic cells | Molecular Transfer, Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| EP-2015780-B1 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | MOLECULAR TRANSFER INC (US) | 2012-12-12 | — | — | EP | disclosed |
| US-20120052574-A1 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | MOLECULAR TRANSFER, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-7915230-B2 | Reagents for transfection of eukaryotic cells | MOLECULAR TRANSFER, INC. (US) | 2011-03-29 | — | — | US | disclosed |
| US-20090023215-A1 | Novel reagents for transfection of eukaryotic cells | MOLECULAR TRANSFER (US) | 2009-01-22 | — | — | US | disclosed |
| EP-2015780-A2 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | Molecular Transfer, Inc. (US) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007130073-A2 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | MOLECULAR TRANSFER, INC. (US) | 2007-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023215-A1 | Novel reagents for transfection of eukaryotic cells | FUS, PHAX, PICALM | KDM4E 4645/4885ALDH1A1 4876/4885FAAH 3351/4885 |
| US-20120052574-A1 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | FUS, PHAX, PICALM | KDM4E 4645/4885ALDH1A1 4876/4885FAAH 3351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.