Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10565223 | 0.81 | CHEK1 (0.41) | NR4A2KDM4ETDP1AURKAPDPK1 | |
| SCHEMBL7170269 | 0.71 | NPY5R (0.35) | KMT2AGAACHEK1FLT3PLK3 | |
| SCHEMBL10567266 | 0.68 | GSK3B (0.47) | DYRK1A | |
| SCHEMBL26851067 | 0.67 | GAA (0.43) | KDM4EAURKAPDPK1TGFBR1ROCK1 | |
| SCHEMBL6322346 | 0.65 | — | — | |
| SCHEMBL10803369 | 0.65 | SLC2A1 (0.44) | NR4A2KDM4ETDP1ROCK1NCF1 | |
| SCHEMBL16946863 | 0.65 | DYRK1A (0.37) | AURKAPDPK1TGFBR1ROCK1AURKB | |
| SCHEMBL30881703 | 0.63 | AURKA (0.35) | AURKAPDPK1TGFBR1ROCK1AURKB | |
| SCHEMBL29209716 | 0.63 | AURKA (0.35) | AURKAPDPK1TGFBR1ROCK1AURKB | |
| SCHEMBL31347094 | 0.63 | DYRK1A (0.39) | PDPK1KMT2AGAADYRK1ACHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003039500-A1 | USE OF A MERTENSIA MARITIMA EXTRACT IN OXIDATION DYEING OF KERATINOUS FIBERS | L'OREAL (FR) | 2003-05-15 | — | — | WO | claimed |