Propylene Oxide

Propylene Oxide

SCHEMBL7175993

CC1CO1.CCCCC1OC1O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SPHK2 Q9NRA0 11/20 0.44
SPHK1 Q9NYA1 10/20 0.44
ALDH1A1 P00352 1/20 0.39
EBP Q15125 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
EPHX1 P07099 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
CYP1A2 P05177 1/20 0.31
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1750705 0.87
SCHEMBL6580103 0.78 SPHK2 (0.50) SPHK2SPHK1ALDH1A1EPHX1
SCHEMBL28264194 0.78 SPHK2 (0.50) SPHK2SPHK1ALDH1A1EPHX1
SCHEMBL6431885 0.78 SPHK2 (0.50) SPHK2SPHK1ALDH1A1EPHX1
SCHEMBL10436732 0.78 SPHK2 (0.50) SPHK2SPHK1ALDH1A1EPHX1
SCHEMBL6664894 0.78 SPHK2 (0.50) SPHK2SPHK1ALDH1A1EPHX1
SCHEMBL3745108 0.78 SPHK2 (0.50) SPHK2SPHK1ALDH1A1EPHX1
Propylene Oxide SCHEMBL9621592 0.73 ALDH1A1 (0.70) SPHK2SPHK1ALDH1A1EBPSIGMAR1
Methane SCHEMBL22499765 0.72 SPHK2 (0.50) SPHK2SPHK1ALDH1A1
Ethylene Glycol SCHEMBL8149806 0.72 SPHK2 (0.46) SPHK2SPHK1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0821876-B1 Stable arylpyrrole particles, process for their preparation and suspension concentrate compositions comprising them BASF AG (DE) 2003-04-23 EP claimed
US-6417372-B2 SPECIFIED RATIO OF TWO POLYMORPHS, GIVEN PARTICLE SIZES; STORAGE STABILITY; PESTICIDAL SUSPENSIONS SUCH AS OF CHLORFENAPYR; PREPARED BY AGING AND MILLING PARTICLES BASF AKTIENGESELLSCHAFT (DE) 2002-07-09 US claimed
US-20010031879-A1 Stable arylpyrrole particles, process for their preparation and suspension concentrate compositions comprising them INTELLECTUAL PROPERTY DEPARTMENT AMERICAN CYANAMID COMPANY 2001-10-18 US claimed
EP-0683979-B1 Suspension concentrate compositions of arylpyrrole insecticidal and acaricidal agents AMERICAN CYANAMID CO (US) 1999-07-14 EP claimed
EP-0821876-A1 Stable arylpyrrole particles, process for their preparation and suspension concentrate compositions comprising them American Cyanamid Company (US) 1998-02-04 EP claimed
EP-0496989-B1 Herbicidal emulsifiable concentrate compositions of imidazolinone and dinitroaniline herbicides AMERICAN CYANAMID CO (US) 1996-12-11 EP claimed
US-5496845-A Suspension concentrate compositions of arylpyrrole insecticidal and acaricidal agents AMERICAN CYANAMID CO. (US) 1996-03-05 US claimed
EP-0683979-A2 Suspension concentrate compositions of arylpyrrole insecticidal and acaricidal agents AMERICAN CYANAMID COMPANY (US) 1995-11-29 EP claimed
US-5270286-A Herbicidal emulsifiable concentrate compositions of imidazolinone herbicides AMERICAN CYANAMID COMPANY (US) 1993-12-14 US claimed
EP-0279068-B1 HERBICIDAL OIL IN WATER COMBINATION COMPOSITIONS OF PENDIMETHALIN AMERICAN CYANAMID COMPANY (US) 1993-04-07 EP claimed
EP-0496989-A1 Herbicidal emulsifiable concentrate compositions of imidazolinone and dinitroaniline herbicides AMERICAN CYANAMID COMPANY (US) 1992-08-05 EP claimed
US-5019150-A Herbicidal oil in water combination compositions of imidazolinone herbicides AMERICAN CYANAMID COMPANY (US) 1991-05-28 US claimed
US-4971617-A NICOTINIC ACID OR QUINOLINECARBOXYLIC ACID DERIVATIVES AMERICAN CYANAMID COMPANY (US) 1990-11-20 US claimed
US-4931089-A Herbicidal oil in water compositions of pendimethalin AMERICAN CYANAMID COMPANY (US) 1990-06-05 US claimed
US-4822405-A AND 2,6-DINITROANILINE HERBICIDES AMERICAN CYANAMID COMPANY (US) 1989-04-18 US claimed
US-4810279-A STORAGE STABLE CONCENTRATES AMERICAN CYANAMID COMPANY (US) 1989-03-07 US claimed
EP-0279068-A2 Herbicidal oil in water combination compositions of pendimethalin AMERICAN CYANAMID COMPANY (US) 1988-08-24 EP claimed
EP-0821876-B1 Stable arylpyrrole particles, process for their preparation and suspension concentrate compositions comprising them BASF AG (DE) 2003-04-23 EP disclosed
US-4810279-A STORAGE STABLE CONCENTRATES AMERICAN CYANAMID COMPANY (US) 1989-03-07 US disclosed
EP-0279068-A2 Herbicidal oil in water combination compositions of pendimethalin AMERICAN CYANAMID COMPANY (US) 1988-08-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031879-A1 Stable arylpyrrole particles, process for their preparation and suspension concentrate compositions comprising them DDT, PARK7, AGPS SPHK2 1288/4885SPHK1 1998/4885ALDH1A1 828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.