SCHEMBL717647

SCHEMBL717647

Oc1ccc(C#Cc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.67
MAPT P10636 2/20 0.56
CA12 O43570 4/20 0.53
CA2 P00918 4/20 0.53
CA9 Q16790 4/20 0.53
CA3 P07451 3/20 0.53
CA14 Q9ULX7 3/20 0.53
CA1 P00915 3/20 0.53
CA4 P22748 2/20 0.53
GLA P06280 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
FFAR1 O14842 4/20 0.50
HNF4A P41235 1/20 0.50
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
CA6 P23280 1/20 0.48
FFAR4 Q5NUL3 1/20 0.47
GRM5 P41594 1/20 0.46
AKR1C2 P52895 1/20 0.46
AKR1C1 Q04828 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18549484 1.00 APP (0.67) APPMAPTCA12CA2CA9
SCHEMBL673609 0.88 APP (0.74) APPMAPTCA12CA2CA9
SCHEMBL14400750 0.88 APP (0.74) APPMAPTCA12CA2CA9
SCHEMBL19026498 0.87 APP (0.57) APPMAPTCA12CA2CA9
SCHEMBL28395598 0.87 MMP3 (0.71) APPMAPTMMP3BCL2L1MEN1
SCHEMBL13283919 0.87 LTA4H (0.68) APPMAPTFFAR1MEN1LMNA
SCHEMBL2114741 0.85 APP (0.92) APPMAPTCA12CA2CA9
SCHEMBL5072017 0.85 LMNA (0.62) APPMAPTCA12CA2CA9
SCHEMBL20211704 0.84 APP (0.60) APPMAPTCA12CA2CA9
SCHEMBL4267409 0.84 APP (0.60) APPMAPTCA12CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132403-A2 UPCYCLING OF POLYARYLETHERSULFONE TO MAKE A REACTIVE MACROMER PRODUCT SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2025-06-26 WO claimed
CN-109734686-B Catalytic synthesis method of 2-substituted benzofuran compound 浙江万里学院 2022-07-01 CN claimed
CN-113416127-A Cross-linkable semi-crystalline polyether-ether-ketone, preparation method and application thereof, polyether-ether-ketone polymer alloy material and preparation method thereof 吉林大学 2021-09-21 CN claimed
CN-107683305-B Microporous polymer composition 联邦科学与工业研究组织 2020-09-18 CN claimed
CN-111363140-A Crosslinkable fluorine-containing polyarylether and preparation method and application thereof 吉林大学 2020-07-03 CN claimed
US-10654985-B2 Microporous polymeric composition COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2020-05-19 US claimed
CN-104936684-B Mixed-matrix polymer composition 联邦科学与工业研究组织 2018-07-03 CN claimed
US-20180142075-A1 MICROPOROUS POLYMERIC COMPOSITION COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2018-05-24 US claimed
EP-3303475-A1 MICROPOROUS POLYMERIC COMPOSITION Commonwealth Scientific and Industrial Research Organisation (AU) 2018-04-11 EP claimed
CN-107683305-A Microporous polymer compositions 联邦科学与工业研究组织 2018-02-09 CN claimed
WO-2010086385-A1 CROSS-LINKABLE AROMATIC POLYCARBONATE NEXAM CHEMICALS AB (SE) 2010-08-05 WO claimed
WO-2010074625-A1 ACETYLENIC AROMATIC POLYETHER NEXAM CHEMICAL AB (SE) 2010-07-01 WO claimed
WO-2010071532-A1 ACETYLENIC PHENOL-ALDEHYDE RESIN NEXAM CHEMICAL AB (SE) 2010-06-24 WO claimed
WO-2010030216-A1 ACETYLENIC POLY(ALKYLENE PHTHALATE) NEXAM CHEMICAL AB (SE) 2010-03-18 WO claimed
CN-100519623-C Fluorinated aromatic polymer and use thereof ASAHI GLASS CO LTD (JP) 2009-07-29 CN claimed
US-6946534-B2 Fluorinated polyethers having perfluorinated aliphatic group and optical waveguide using the same Kim, Mi-Hwa (KR) 2005-09-20 US claimed
US-6512076-B2 Condensation polymerization of a pentafluorophenyl sulfide and pentafluorophenyl sulfone monomer with dihydroxy monomer; heat, solvent and water resistance; use to make waveguides KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2003-01-28 US claimed
US-20020115815-A1 Poly (arylene ether sulfide) and poly (arylene ether sulfone) for optical device and method for preparing the same KWAGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2002-08-22 US claimed
EP-1219665-A2 Poly (arylene ether sulfide) and poly (arylene ether sulfone) for optical device and method for preparing the same Kwangju Institute of Science and Technology (KR) 2002-07-03 EP claimed
US-20020057882-A1 Fluorinated polyethers having perfluorinated aliphatic group and optical waveguide using the same ZEN PHOTONICS CO. LTD. (KR) 2002-05-16 US claimed