Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20414337 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTHSP90AA1KMT2AHIF1A | |
| SCHEMBL28919959 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTHSP90AA1KMT2AHIF1A | |
| SCHEMBL9683260 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTHSP90AA1KMT2AHIF1A | |
| SCHEMBL673965 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTHSP90AA1KMT2AHIF1A | |
| SCHEMBL8859065 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2ATDP1RAB9A | |
| SCHEMBL9683262 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTHSP90AA1KMT2AHIF1A | |
| SCHEMBL7093376 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AMAPK1TDP1 | |
| SCHEMBL2845203 | 0.76 | AKR1C1 (0.45) | ALDH1A1MAPTKMT2ARECQLMAPK1 | |
| SCHEMBL10933652 | 0.74 | KMT2A (0.46) | ALDH1A1MAPTKMT2ARECQLMAPK1 | |
| SCHEMBL27490875 | 0.74 | KMT2A (0.46) | ALDH1A1MAPTKMT2ARECQLMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0622381-B1 | Anionic polymerization initiators and reduced hysteresis products therefrom | BRIDGESTONE CORP (JP) | 1998-07-29 | — | — | EP | claimed |
| EP-0451603-B1 | Elastomers and products having reduced hysteresis | BRIDGESTONE FIRESTONE INC (US) | 1996-02-07 | — | — | EP | claimed |
| EP-0622381-A1 | Anionic polymerization initiators and reduced hysteresis products therefrom | BRIDGESTONE CORPORATION (JP) | 1994-11-02 | — | — | EP | claimed |
| US-5354822-A | Endcapping the addition polymerization with a reaction product of an aldimines, a ketimines, a secondary amines and an organo lithium compound prior quenching | BRIDGESTONE/FIRESTONE, INC. (US) | 1994-10-11 | — | — | US | claimed |
| US-5268413-A | Blend of functionalized polymer and organolithium compound | BRIDGESTONE/FIRESTONE, INC. (US) | 1993-12-07 | — | — | US | claimed |
| US-5153159-A | ELASTOMERS AND PRODUCTS HAVING REDUCED HYSTERESIS | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-10-06 | — | — | US | claimed |
| EP-0451603-A2 | Elastomers and products having reduced hysteresis | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-10-16 | — | — | EP | claimed |
| EP-0890580-B1 | Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds | BRIDGESTONE CORP (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6228908-B1 | Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds | BRIDGESTONE CORPORATION (JP) | 2001-05-08 | — | — | US | disclosed |
| US-6008295-A | FIRST COUPLING THE LIVING DIENE POLYMER OR COPOLYMER CHAINS OBTAINED BY ANIONIC POLYMERIZATION WITH A TIN HALIDE COUPLING AGENT AND THEN TERMINATING THE REMAINING LIVING POLYMER OR COPOLYMER CHAINS WITH A HYDROCARBOXYSILANE; TIRE TREADS | BRIDGESTONE CORPORATION (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0890580-A1 | Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds | Bridgestone Corporation (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0572792-B1 | Tire tread composition | BRIDGESTONE CORP (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5698646-A | ANIONIC POLYMERIZATION OF BUTADIENE-STYRENE COPOLYMER USING LITHIUM COMPOUND AND CHELATE COMPOUND | BRIDGESTONE CORPORATION (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0510410-A1 | Diene polymers and copolymers jumped by partial coupling and terminated with a substituted imine | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-10-28 | — | — | EP | disclosed |
| US-5153159-A | ELASTOMERS AND PRODUCTS HAVING REDUCED HYSTERESIS | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-10-06 | — | — | US | disclosed |
| US-5153271-A | Conjugated homo- or copolyenes, aromatic olefin copolymers endcapped by benzonitrile(or derivataives), for reduced hystersis in tire treads | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-10-06 | — | — | US | disclosed |
| US-5109907-A | Tire treads with reduced rolling resistance | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-05-05 | — | — | US | disclosed |
| US-5066729-A | Tire Treads | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0451603-A2 | Elastomers and products having reduced hysteresis | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-10-16 | — | — | EP | disclosed |
| EP-0451604-A2 | Diene polymers and copolymers terminated by reaction with n-alkyl and n-aryl imines | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-10-16 | — | — | EP | disclosed |