SCHEMBL673965

SCHEMBL673965

CN(C)C(=CCN)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
MAPT P10636 1/20 0.43
AOC3 Q16853 2/20 0.38
MAOB P27338 1/20 0.38
HSP90AA1 P07900 1/20 0.38
KMT2A Q03164 1/20 0.37
HIF1A Q16665 1/20 0.37
RECQL P46063 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8773365 0.81 SIGMAR1 (0.42) ALDH1A1MAPTMAOB
SCHEMBL673022 0.80 ALDH1A1 (0.44) ALDH1A1MAPTKMT2A
SCHEMBL7180326 0.78 ALDH1A1 (0.46) ALDH1A1MAPTAOC3MAOBHSP90AA1
SCHEMBL20414337 0.78 ALDH1A1 (0.50) ALDH1A1MAPTMAOBHSP90AA1KMT2A
SCHEMBL9790466 0.74 KDM1A (0.46)
SCHEMBL9790470 0.74 KDM1A (0.46)
SCHEMBL9790462 0.74 KDM1A (0.46)
SCHEMBL1286537 0.73 CHRNB2 (0.47) AOC3MAOB
SCHEMBL8527109 0.73 NFE2L2 (0.43) MAPTAOC3MAOBKMT2ARECQL
Hydrochloric Acid SCHEMBL9790500 0.72 KDM1A (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1873168-B1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORP (JP) 2012-12-12 EP claimed
US-7968652-B2 Modified conjugated diene copolymer, rubber compositions and tires BRIDGESTONE CORPORATION (JP) 2011-06-28 US claimed
US-7671136-B2 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2010-03-02 US claimed
US-20090292043-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORPORATION (JP) 2009-11-26 US claimed
EP-1873168-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES Bridgestone Corporation (JP) 2008-01-02 EP claimed
US-20060025539-A1 Modified polymers prepared with lanthanide-based catalysts OZAWA YOICHI 2006-02-02 US claimed
US-6977281-B1 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2005-12-20 US claimed
EP-1237935-A1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS Bridgestone Corporation (JP) 2002-09-11 EP claimed
WO-2001034659-A1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS BRIDGESTONE CORPORATION (JP) 2001-05-17 WO claimed
CN-111051361-B Rubber composition 株式会社LG化学 2023-06-20 CN disclosed
US-11680153-B2 Rubber composition LG CHEM, LTD. 2023-06-20 US disclosed
EP-3715388-B1 MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD FOR PREPARING THE SAME LG CHEMICAL LTD (KR) 2023-04-26 EP disclosed
US-11421053-B2 Conjugated diene-based polymer and method for preparing the same LG CHEM, LTD. 2022-08-23 US disclosed
US-11384178-B2 2022-07-12 US disclosed
US-5310798-A Tire treads BRIDGESTONE/FIRESTONE, INC. (US) 1994-05-10 US disclosed
US-5227431-A DIENE POLYMERS AND COPOLYMERS JUMPED BY PARTIAL CROSSLINKING AND TERMINATED WITH A SUBSTITUTED IMINE BRIDGESTONE/FIRESTONE, INC. (US) 1993-07-13 US disclosed
EP-0510410-A1 Diene polymers and copolymers jumped by partial coupling and terminated with a substituted imine BRIDGESTONE/FIRESTONE, INC. (US) 1992-10-28 EP disclosed
US-5109907-A Tire treads with reduced rolling resistance BRIDGESTONE/FIRESTONE, INC. (US) 1992-05-05 US disclosed
US-5066729-A Tire Treads BRIDGESTONE/FIRESTONE, INC. (US) 1991-11-19 US disclosed
EP-0451604-A2 Diene polymers and copolymers terminated by reaction with n-alkyl and n-aryl imines BRIDGESTONE/FIRESTONE, INC. (US) 1991-10-16 EP disclosed