Sugi Predict

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SCHEMBL7185570

SCHEMBL7185570

Cc1cc(C)c(C(=O)P(=O)(c2ccccc2)C(C)C)c(C)c1C

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ KMT2A Q03164 4/20 0.33
▸ MEN1 O00255 3/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ POLB P06746 2/20 0.32
▸ CA2 P00918 1/20 0.32
▸ CA4 P22748 1/20 0.32
▸ CA5A P35218 1/20 0.32
▸ TSHR P16473 1/20 0.31
▸ USP2 O75604 1/20 0.31
▸ ESR1 P03372 1/20 0.31
▸ LDHA P00338 1/20 0.31
▸ HSD17B10 Q99714 2/20 0.31
▸ GFER P55789 1/20 0.31
▸ MMP1 P03956 1/20 0.31
▸ MMP3 P08254 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ CRHBP P24387 1/20 0.31
▸ CRHR2 Q13324 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7188459 0.87 POLB (0.35) ALDH1A1L3MBTL1KMT2AMEN1POLB
SCHEMBL7182208 0.85 ALDH1A1 (0.38) ALDH1A1L3MBTL1KMT2AMEN1POLB
SCHEMBL7181616 0.81 KMT2A (0.36) ALDH1A1KMT2AMEN1KDM4EPOLB
SCHEMBL7190113 0.81 L3MBTL1 (0.40) ALDH1A1L3MBTL1POLBCA2CA4
SCHEMBL3243623 0.81 KMT2A (0.37) ALDH1A1L3MBTL1KMT2AMEN1KDM4E
SCHEMBL7179793 0.81 LMNA (0.37) ALDH1A1L3MBTL1KMT2AMEN1TSHR
SCHEMBL7177683 0.80 KMT2A (0.38) ALDH1A1KMT2AMEN1KDM4EPOLB
SCHEMBL7180632 0.80 ALDH1A1 (0.38) ALDH1A1L3MBTL1KMT2AMEN1KDM4E
SCHEMBL7180464 0.79 KMT2A (0.34) ALDH1A1KMT2AMEN1KDM4EPOLB
SCHEMBL7174855 0.79 GFER (0.35) ALDH1A1KMT2AMEN1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 ALDH1A1 3416/4885L3MBTL1 302/4885KMT2A 1586/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 ALDH1A1 3984/4885L3MBTL1 126/4885KMT2A 956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.