Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189493 | 0.92 | ALDH1A1 (0.60) | P2RX7ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL7181153 | 0.91 | TAS1R3 (0.63) | P2RX7ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL7187483 | 0.91 | ALDH1A1 (0.68) | P2RX7ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL4048976 | 0.78 | NPC1 (0.83) | P2RX7ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL936525 | 0.78 | TAS1R3 (0.57) | P2RX7ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL13544567 | 0.78 | GAA (0.58) | P2RX7ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL534385 | 0.78 | P2RX7 (1.00) | P2RX7ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL3170903 | 0.78 | P2RX7 (0.57) | P2RX7ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL2747078 | 0.78 | DRD4 (0.67) | ALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL1987660 | 0.78 | TAS1R3 (0.64) | P2RX7ALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366116-A2 | POLYPROPYLENE RESIN COMPOSITIONS | Ciba SC Holding AG (CH) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002046300-A2 | POLYPROPYLENE RESIN COMPOSITIONS | CIBA SPECIALITY CHEMICALS HOLDING INC. (CH) | 2002-06-13 | — | — | WO | disclosed |