Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7181266 | 0.88 | SMN1; SMN2 (0.68) | SMN1; SMN2ESR1ESR2MEN1KMT2A | |
| SCHEMBL9085314 | 0.88 | SMN1; SMN2 (0.68) | SMN1; SMN2ESR1ESR2MEN1KMT2A | |
| SCHEMBL9087363 | 0.86 | AGER (0.53) | SMN1; SMN2ESR1ESR2ADRB2LMNA | |
| SCHEMBL7183961 | 0.86 | AGER (0.53) | SMN1; SMN2ESR1ESR2ADRB2LMNA | |
| SCHEMBL9089267 | 0.86 | SMN1; SMN2 (0.70) | SMN1; SMN2MEN1KMT2ALMNASLC6A2 | |
| SCHEMBL580415 | 0.86 | POLB (0.60) | SMN1; SMN2MEN1KMT2AADRB2LMNA | |
| SCHEMBL4424042 | 0.86 | SMN1; SMN2 (0.70) | SMN1; SMN2MEN1KMT2ALMNASLC6A2 | |
| SCHEMBL7176489 | 0.86 | SMN1; SMN2 (0.70) | SMN1; SMN2MEN1KMT2ALMNASLC6A2 | |
| SCHEMBL7181502 | 0.83 | CASR (0.62) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7178764 | 0.80 | L3MBTL1 (0.51) | SMN1; SMN2IDO1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510519-A | OPTICAL RESOLUTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-04-23 | — | — | US | claimed |
| EP-0508307-B1 | Optically active secondary amine compound; process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound | SUMITOMO CHEMICAL CO (JP) | 1995-11-29 | — | — | EP | claimed |
| US-5298660-A | Compound containing an assymetrical carbon atom | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-03-29 | — | — | US | claimed |
| EP-0508307-A2 | Optically active secondary amine compound; process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-10-14 | — | — | EP | claimed |
| EP-0933349-B1 | Method for producing optically active chrysanthemic acid | SUMITOMO CHEMICAL CO (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-20020123645-A1 | Method for producing optically active chrysanthemic acid | SUMITOMO CHEMICAL COMPANY, LIMITED | 2002-09-05 | — | — | US | disclosed |
| EP-1236708-A1 | Method for producing optically active chrysanthemic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6268525-B1 | REACTING CHRYSANTHEMIC ACID HAVING TRANS ISOMER WITH OPTICALLY ACTIVE AMINE TO OPTICALLY RESOLVE CHRYSANTHEMIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-07-31 | — | — | US | disclosed |
| EP-0933349-A1 | Method for producing optically active chrysanthemic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |
| US-5510519-A | OPTICAL RESOLUTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0508307-B1 | Optically active secondary amine compound; process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound | SUMITOMO CHEMICAL CO (JP) | 1995-11-29 | — | — | EP | disclosed |
| US-5298660-A | Compound containing an assymetrical carbon atom | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-03-29 | — | — | US | disclosed |
| EP-0508307-A2 | Optically active secondary amine compound; process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-10-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020123645-A1 | Method for producing optically active chrysanthemic acid | ENO1, CYP8B1, CRYAA | SMN1; SMN2 3784/4885IDO1 2938/4885ESR1 733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.