Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29156290 | 0.70 | SIGMAR1 (0.54) | MAPTL3MBTL1ALDH1A1CYP2D6MEN1 | |
| SCHEMBL29156287 | 0.70 | SIGMAR1 (0.54) | MAPTL3MBTL1ALDH1A1CYP2D6MEN1 | |
| SCHEMBL7182597 | 0.69 | OPRM1 (0.42) | ALDH1A1MEN1KMT2AATM | |
| SCHEMBL23023178 | 0.69 | SIGMAR1 (0.52) | MAPTALDH1A1MEN1KMT2ASIGMAR1 | |
| SCHEMBL1790979 | 0.69 | SCN9A (0.57) | MAPTL3MBTL1SIGMAR1 | |
| SCHEMBL411692 | 0.69 | SCN9A (0.57) | MAPTL3MBTL1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL5966887 | 0.67 | SCN9A (0.56) | MAPTL3MBTL1SIGMAR1 | |
| SCHEMBL106076 | 0.67 | MAPT (0.67) | MAPTL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL914510 | 0.67 | MAPT (0.67) | MAPTL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL106075 | 0.67 | MAPT (0.67) | MAPTL3MBTL1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294700-A2 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000631-A2 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |