Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25650262 | 0.84 | RAPGEF4 (0.41) | TRPA1MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL18403913 | 0.81 | RAPGEF4 (0.38) | MAPTALDH1A1TDP1L3MBTL1RAPGEF4 | |
| SCHEMBL22996779 | 0.78 | ALDH1A1 (0.43) | MAPTALDH1A1TDP1L3MBTL1RAPGEF4 | |
| SCHEMBL14924464 | 0.78 | NOS2 (0.41) | RAPGEF4CYP2C19HTT | |
| SCHEMBL12963494 | 0.77 | RAPGEF4 (0.50) | MAPTALDH1A1TDP1L3MBTL1RAPGEF4 | |
| SCHEMBL19121210 | 0.76 | TRPA1 (0.44) | TRPA1MAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8285560 | 0.75 | THRB (0.57) | TRPA1MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL24348160 | 0.72 | RAPGEF4 (0.52) | RAPGEF4CYP3A4 | |
| SCHEMBL10625450 | 0.72 | TRPA1 (0.49) | TRPA1MAPTRAPGEF4CYP1A2CYP3A4 | |
| SCHEMBL1521699 | 0.72 | RAPGEF4 (0.35) | TRPA1MAPTALDH1A1RAPGEF4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150158909-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158909-A1 | ANTI-VIRAL COMPOUNDS | HAVCR2, EIF2AK2, MAVS | TRPA1 3200/4885MAPT 2328/4885ALDH1A1 1955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.