Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.76 |
| ▸ | CA1 | P00915 | 10/20 | 0.69 |
| ▸ | CA2 | P00918 | 10/20 | 0.69 |
| ▸ | CA9 | Q16790 | 10/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213633 | 0.86 | PTGS2 (1.00) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL13239860 | 0.82 | CA1 (0.70) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL8015867 | 0.82 | PTGS2 (0.65) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL3867856 | 0.81 | PTGS2 (0.78) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL3864236 | 0.81 | PTGS2 (0.90) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL6344401 | 0.81 | CA9 (1.00) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL14732172 | 0.80 | CA9 (0.68) | PTGS2CA1CA2CA9 | |
| SCHEMBL8689665 | 0.79 | CA9 (1.00) | PTGS2CA1CA2CA9 | |
| SCHEMBL13352312 | 0.79 | CA1 (0.60) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL9522392 | 0.79 | RXRA (0.81) | PTGS2L3MBTL1MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854723-B1 | SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR USE IN VETERINARY THERAPIES AS ANTIINFLAMMATORY AGENTS | SEARLE & CO (US) | 2003-04-23 | — | — | EP | claimed |