Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.57 |
| ▸ | TOP2A | P11388 | 8/20 | 0.53 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Meridine SCHEMBL2926298 | 0.81 | TERT (0.60) | TERTTOP2AKDM4EPOLBHPGD | |
| SCHEMBL7189639 | 0.81 | TERT (0.60) | TERTTOP2AKDM4EHPGDMAOA | |
| SCHEMBL6408305 | 0.81 | TERT (0.60) | TERTTOP2AKDM4EALDH1A1HPGD | |
| SCHEMBL7190567 | 0.80 | TERT (0.57) | TERTTOP2AKDM4EPOLBHPGD | |
| SCHEMBL6866314 | 0.77 | MAOA (0.37) | KDM4EALDH1A1POLBGAACNR2 | |
| SCHEMBL7184194 | 0.77 | TERT (0.56) | TERTTOP2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7186247 | 0.75 | TOP2A (0.75) | TERTTOP2AALDH1A1GAAMAOA | |
| Trifluoroacetic Acid SCHEMBL7185106 | 0.73 | TERT (0.55) | TERTTOP2ACNR2 | |
| SCHEMBL7215902 | 0.73 | TERT (0.57) | TERTTOP2AKDM4EPOLBMAOA | |
| SCHEMBL6409035 | 0.72 | HTT (0.42) | TOP2AKDM4EALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583150-B1 | Cytotoxic propertie; antitumor; pyrido-(3,2-g)quinoline-5,10-diones; benzo(b)pyrido(4,3,2-de)(1,7)-phenanthroline-8-ones | LABORATORIE L. LAFON (FR) | 2003-06-24 | — | — | US | claimed |
| US-6583150-B1 | Cytotoxic propertie; antitumor; pyrido-(3,2-g)quinoline-5,10-diones; benzo(b)pyrido(4,3,2-de)(1,7)-phenanthroline-8-ones | LABORATORIE L. LAFON (FR) | 2003-06-24 | — | — | US | disclosed |