Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 10/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 1.00 |
| ▸ | BACE1 | P56817 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | CYP2E1 | P05181 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | CYP2B6 | P20813 | 1/20 | 1.00 |
| ▸ | CYP3A5 | P20815 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.81 |
| ▸ | ACHE | P22303 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bergamottin SCHEMBL14029418 | 1.00 | CYP3A4 (1.00) | CYP3A4TDP1BACE1ALDH1A1KDM4E | |
| Bergamottin SCHEMBL29556462 | 1.00 | CYP3A4 (1.00) | CYP3A4TDP1BACE1ALDH1A1KDM4E | |
| Bergamottin SCHEMBL569529 | 1.00 | CYP3A4 (1.00) | CYP3A4TDP1BACE1ALDH1A1KDM4E | |
| Isoimperatorin SCHEMBL15090959 | 0.90 | ALDH1A1 (1.00) | CYP3A4TDP1BACE1ALDH1A1KDM4E | |
| Notopterol SCHEMBL28964767 | 0.85 | BACE1 (1.00) | CYP3A4TDP1BACE1ALDH1A1KDM4E | |
| Notopterol SCHEMBL30888273 | 0.85 | BACE1 (1.00) | CYP3A4TDP1BACE1ALDH1A1KDM4E | |
| 6',7'-Epoxybergamottin SCHEMBL28859461 | 0.84 | CYP3A4 (0.74) | CYP3A4TDP1BACE1ALDH1A1KDM4E | |
| SCHEMBL30375774 | 0.84 | CYP3A4 (0.72) | CYP3A4TDP1BACE1ALDH1A1KDM4E | |
| 6',7'-Epoxybergamottin SCHEMBL29419949 | 0.84 | CYP3A4 (0.74) | CYP3A4TDP1BACE1ALDH1A1KDM4E | |
| Dihydroxybergamottin SCHEMBL30173389 | 0.82 | CYP3A4 (1.00) | CYP3A4TDP1BACE1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4737898-A2 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | EMP Biotech GmbH (DE) | 2026-05-06 | — | — | EP | disclosed |
| US-20260042797-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | EMP BIOTECH GMBH (DE) | 2026-02-12 | — | — | US | disclosed |
| US-12344633-B2 | Separation and isolation of nucleic acids using affinity ligands bound to a solid surface | EMP BIOTECH GMBH (DE) | 2025-07-01 | — | — | US | disclosed |
| CN-115969891-B | Fructus cnidii total extract and application and map construction method thereof | 杨利平 | 2025-01-21 | — | — | CN | disclosed |
| US-20240389587-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS | INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (INRAE) (FR) | 2024-11-28 | — | — | US | disclosed |
| US-20240325479-A1 | Total extract of Fructus Cnidii and its application and map construction method | YANG LIPING (CN) | 2024-10-03 | — | — | US | disclosed |
| CN-117233298-A | Metabolic-chemistry-based exocarpium citri rubrum year identification method | 中国检验检疫科学研究院 | 2023-12-15 | — | — | CN | disclosed |
| EP-4186367-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS | Institut national de recherche pour l'agriculture, l'alimentation et l'environnement (INRAE) (FR) | 2023-05-31 | — | — | EP | disclosed |
| CN-115969891-A | Fructus cnidii total extract and application and map construction method thereof | 杨利平 | 2023-04-18 | — | — | CN | disclosed |
| CN-115671096-A | Application of 6-methoxy angelicin and structural analogue thereof | 西北工业大学 | 2023-02-03 | — | — | CN | disclosed |
| WO-2021105887-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | EMP BIOTECH GMBH (DE) | 2021-06-03 | — | — | WO | disclosed |
| US-20210155657-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | EMP BIOTECH GMBH (DE) | 2021-05-27 | — | — | US | disclosed |
| CN-107383040-B | A method of isolating and purifying bergamot element from early fragrant shaddock oil vacuole layer | 浙江大学 | 2019-06-07 | — | — | CN | disclosed |
| EP-1007034-B1 | COMPOSITIONS CONTAINING BERGAMOTTIN FOR INCREASING THE ORAL BIOAVAILABILITY OF PHARMACEUTICAL AGENTS | WARNER LAMBERT CO (US) | 2003-11-05 | — | — | EP | disclosed |
| US-6509371-B1 | Compositions containing Bergamottin for increasing the oral bioavailability of pharmaceutical agents | WARNER-LAMBERT COMPANY | 2003-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210155657-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | ADAR, SSBP1, POLRMT | CYP3A4 4878/4885TDP1 560/4885BACE1 4814/4885 |
| US-12344633-B2 | Separation and isolation of nucleic acids using affinity ligands bound to a solid surface | ADAR, SSBP1, POLRMT | CYP3A4 4878/4885TDP1 560/4885BACE1 4814/4885 |
| US-20260042797-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | POLM, SSBP1, POLRMT | CYP3A4 3699/4885TDP1 537/4885BACE1 4817/4885 |
| US-20240389587-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS | XBP1, ERN1, ERN2 | CYP3A4 2585/4885TDP1 1759/4885BACE1 809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.