Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12858625 | 0.84 | KMT2A (0.65) | TDP1ALDH1A1HTTKDM4EATM | |
| SCHEMBL10896432 | 0.83 | TDP1 (0.52) | TDP1ALDH1A1HTTKDM4EATM | |
| SCHEMBL2916925 | 0.79 | TDP1 (0.59) | TDP1ALDH1A1HTTKDM4EATM | |
| SCHEMBL10896965 | 0.77 | TDP1 (0.46) | TDP1ALDH1A1HTTKDM4EATM | |
| SCHEMBL7181153 | 0.77 | TAS1R3 (0.63) | ALDH1A1HTTKDM4ELMNATAS1R3 | |
| SCHEMBL12858327 | 0.77 | ALDH1A1 (0.55) | TDP1ALDH1A1HTTKDM4EATM | |
| SCHEMBL7181787 | 0.74 | P2RX7 (0.64) | ALDH1A1HTTKDM4EKMT2ALMNA | |
| SCHEMBL14296414 | 0.74 | ALDH1A1 (0.63) | TDP1ALDH1A1HTTKDM4EATM | |
| SCHEMBL3455698 | 0.73 | HPGD (0.62) | TDP1ALDH1A1HTTKDM4EATM | |
| SCHEMBL1555269 | 0.73 | ALDH1A1 (0.61) | TDP1ALDH1A1HTTKDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366116-A2 | POLYPROPYLENE RESIN COMPOSITIONS | Ciba SC Holding AG (CH) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002046300-A2 | POLYPROPYLENE RESIN COMPOSITIONS | CIBA SPECIALITY CHEMICALS HOLDING INC. (CH) | 2002-06-13 | — | — | WO | disclosed |