SCHEMBL7183309

SCHEMBL7183309

Nc1ccc(C(=O)c2ccc(N)cc2Cl)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.54
MAPT P10636 4/20 0.50
RAB9A P51151 2/20 0.50
JAK2 O60674 1/20 0.47
TYK2 P29597 1/20 0.47
MAPK13 O15264 1/20 0.47
MAPK12 P53778 1/20 0.47
MAPK11 Q15759 1/20 0.47
MAPK14 Q16539 1/20 0.47
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CYP3A4 P08684 3/20 0.45
TSHR P16473 2/20 0.45
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 2/20 0.44
THRB P10828 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
CASP1 P29466 1/20 0.44
RECQL P46063 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1149168 0.93 SRD5A2 (0.60) SRD5A2MAPTRAB9AJAK2TYK2
SCHEMBL29088628 0.90 MAPT (0.51) SRD5A2MAPTRAB9AJAK2TYK2
SCHEMBL3531609 0.90 SRD5A2 (0.49) SRD5A2MAPTRAB9AJAK2TYK2
SCHEMBL5963546 0.89 MAPK13 (0.58) SRD5A2MAPTJAK2TYK2MAPK13
SCHEMBL6654858 0.89 SRD5A2 (0.70) SRD5A2MAPTRAB9ATSHRALDH1A1
SCHEMBL7090488 0.88 JAK2 (0.53) SRD5A2MAPTJAK2TYK2CA1
SCHEMBL8309451 0.86 JAK2 (0.61) SRD5A2MAPTRAB9AJAK2TYK2
SCHEMBL7189678 0.86 ALDH1A1 (0.60) SRD5A2MAPTRAB9AJAK2TYK2
SCHEMBL30574108 0.85 MAPT (0.73) MAPTRAB9ACA1CA2ALDH1A1
SCHEMBL11711133 0.85 MAPT (0.73) MAPTRAB9ACA1CA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110430937-A Diblock copolymer vesicles and separation membranes comprising aquaporin water channels and methods of making and using the same AQUAPORIN AS 2019-11-08 CN disclosed
CN-110049810-A Self-assembled polymer vesicle structure with functional molecules 水通道蛋白有限公司 2019-07-23 CN disclosed
CN-106393876-B Metal-coated laminated plate, preparation method thereof and method for preparing flexible circuit board by using metal-coated laminated plate 长兴材料工业股份有限公司 2019-05-14 CN disclosed
CN-107312173-A Polyimide precursor and use thereof 长兴材料工业股份有限公司 2017-11-03 CN disclosed
CN-104211881-B Organic-inorganic hybrid material film and method for producing same 联茂电子股份有限公司 2017-04-12 CN disclosed
CN-106393876-A Metal-coated laminated plate, preparation method thereof and method for preparing flexible circuit board by using metal-coated laminated plate 长兴材料工业股份有限公司 2017-02-15 CN disclosed
CN-104211881-A Organic-inorganic hybrid material film and method for producing same ITEQ CORP 2014-12-17 CN disclosed
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed