SCHEMBL7183337

SCHEMBL7183337

O=Cc1ccc2ccccc2c1N(N=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
ALOX15 P16050 1/20 0.47
PTPN1 P18031 4/20 0.39
POLB P06746 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ERN1 O75460 1/20 0.36
CYP2A6 P11509 2/20 0.33
MAPT P10636 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
EIF4H Q15056 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
LMNA P02545 1/20 0.31
THRB P10828 1/20 0.31
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7545409 0.84 PTPN1 (0.38) ALDH1A1ALOX15PTPN1POLBMEN1
SCHEMBL7543590 0.80 ERN1 (0.42) ALDH1A1PTPN1POLBMEN1KMT2A
SCHEMBL7191201 0.78 ALDH1A1 (0.50) ALDH1A1ALOX15PTPN1POLBMEN1
SCHEMBL7535670 0.76 WDR5 (0.51) ALDH1A1ALOX15PTPN1MEN1KMT2A
SCHEMBL28141984 0.74 POLB (0.45) ALDH1A1PTPN1POLBMEN1KMT2A
SCHEMBL7186507 0.72 PTPN1 (0.45) ALDH1A1PTPN1POLBMEN1KMT2A
SCHEMBL4168193 0.70 ALDH1A1 (0.57) ALDH1A1ALOX15CYP2A6TDP1TSHR
SCHEMBL7191202 0.70 ALDH1A1 (0.57) ALDH1A1ALOX15POLBMEN1KMT2A
SCHEMBL7535160 0.69 KMT2A (0.38) ALDH1A1ALOX15PTPN1POLBMEN1
SCHEMBL21044875 0.68 ERN1 (0.43) ALDH1A1PTPN1POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 EP disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 ALDH1A1 1488/4885ALOX15 1802/4885PTPN1 2904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.