Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.41 |
| ▸ | CTSL | P07711 | 5/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045974 | 0.86 | CTSS (0.43) | CTSSCTSLCTSBLMNAMAPT | |
| SCHEMBL6464253 | 0.79 | TSHR (0.37) | CTSSLMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL7043453 | 0.74 | LMNA (0.43) | CTSSCTSLLMNAMAPTMEN1 | |
| SCHEMBL6466282 | 0.74 | LMNA (0.39) | CTSSLMNAMAPTMEN1KMT2A | |
| SCHEMBL6467035 | 0.72 | LMNA (0.47) | LMNAMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL6063094 | 0.72 | CTSS (0.47) | CTSSLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL6462894 | 0.71 | MEN1 (0.38) | CTSSCTSLCTSBLMNAMAPT | |
| SCHEMBL7047935 | 0.71 | LMNA (0.37) | CTSSLMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL7048360 | 0.71 | HTT (0.45) | LMNAMAPTMEN1KMT2AHTT | |
| SCHEMBL7049029 | 0.70 | RAB9A (0.38) | CTSSCTSLCTSBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |