Sugi Predict

Sugi Predict / Compounds / SCHEMBL7183567

SCHEMBL7183567

SCHEMBL7183567

Cc1cccc(C)c1C(=O)[PH](=O)c1c(C)cc(C)c(C(=O)c2ccccc2)c1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ ALDH1A1 P00352 6/20 0.36
▸ MAPT P10636 3/20 0.36
▸ LMNA P02545 1/20 0.36
▸ BCL2L1 Q07817 1/20 0.35
▸ HPGD P15428 2/20 0.35
▸ HTT P42858 2/20 0.35
▸ CYP3A4 P08684 2/20 0.34
▸ CYP2C9 P11712 2/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ CYP2D6 P10635 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ PBRM1 Q86U86 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ GRM6 O15303 1/20 0.34
▸ CNR1 P21554 1/20 0.33
▸ CNR2 P34972 1/20 0.33
▸ MAPK14 Q16539 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7182415 0.91 ALDH1A1 (0.39) ATMTDP1L3MBTL1ALDH1A1MAPT
SCHEMBL7180520 0.89 ALDH1A1 (0.36) ATMTDP1L3MBTL1ALDH1A1MAPT
SCHEMBL7187402 0.88 LMNA (0.37) ATMTDP1L3MBTL1ALDH1A1MAPT
SCHEMBL7190475 0.88 ALDH1A1 (0.40) ATMTDP1L3MBTL1ALDH1A1MAPT
SCHEMBL7183829 0.86 POLB (0.38) ATMTDP1L3MBTL1ALDH1A1MAPT
SCHEMBL7188495 0.86 CA12 (0.41) ATML3MBTL1ALDH1A1MAPTLMNA
SCHEMBL7186789 0.85 NR1H2 (0.37) ATMTDP1L3MBTL1ALDH1A1MAPT
SCHEMBL7177292 0.84 HTT (0.38) ATMTDP1L3MBTL1ALDH1A1MAPT
SCHEMBL7178033 0.84 HTT (0.40) ATMTDP1L3MBTL1ALDH1A1MAPT
SCHEMBL7178047 0.81 MAPT (0.38) ATML3MBTL1ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 ATM 2823/4885TDP1 4234/4885L3MBTL1 302/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 ATM 2935/4885TDP1 4275/4885L3MBTL1 126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.