Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 5/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7181669 | 0.89 | APP (0.37) | NPC1SMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL6437480 | 0.86 | NPC1 (0.41) | NPC1SMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL7191185 | 0.84 | NPC1 (0.44) | NPC1SMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL563466 | 0.79 | NPC1 (0.50) | NPC1SMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL6754426 | 0.78 | APP (0.55) | NPC1SMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL7185943 | 0.75 | NPC1 (0.40) | NPC1SMN1; SMN2KDM4EMEN1ALDH1A1 | |
| Benzene SCHEMBL28228276 | 0.75 | CA4 (0.41) | SMN1; SMN2KDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL6036840 | 0.75 | TSHR (0.45) | NPC1SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL30264142 | 0.72 | ALDH1A1 (0.41) | NPC1SMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL332012 | 0.72 | ALDH1A1 (0.41) | NPC1SMN1; SMN2KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276807-A1 | CURABLE SILICONE RESIN COMPOSITION AND REACTIVE SILICON COMPOUNDS | Dow Corning Corporation (US) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001083608-A1 | CURABLE SILICONE RESIN COMPOSITION AND REACTIVE SILICON COMPOUNDS | DOW CORNING CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |