SCHEMBL20123183

SCHEMBL20123183

OC1c2ccccc2-c2cccc(Br)c21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
NCOR2 Q9Y618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7183892 0.90 ALDH1A1 (0.39) ALDH1A1MEN1KMT2AKDM4ETP53
SCHEMBL24730384 0.79 GABRA1 (0.41) ALDH1A1MEN1KMT2AKDM4ETP53
SCHEMBL784718 0.78 MAPK1 (0.37) ALDH1A1MEN1KMT2AHDAC3HDAC4
SCHEMBL1261847 0.78 MEN1 (0.45) ALDH1A1MEN1KMT2AKDM4ETP53
SCHEMBL11783880 0.78 HTR2B (0.51) ALDH1A1MEN1KMT2AKDM4ETP53
SCHEMBL28327267 0.76 GPR3 (0.38) ALDH1A1MEN1KMT2ACYP3A4CYP2D6
SCHEMBL18243596 0.76 HDAC3 (0.37) ALDH1A1MEN1KMT2AHDAC3HDAC4
SCHEMBL6018181 0.76 MAPK1 (0.35) ALDH1A1MEN1KMT2AHDAC3HDAC4
SCHEMBL7324096 0.76 CHRNB2 (0.45) ALDH1A1MEN1KMT2AKDM4ETP53
SCHEMBL18456445 0.76 KDM4E (0.39) ALDH1A1MEN1KMT2AKDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104387314-B Carbazole derivates, and light-emitting component, luminescent device and electronic device using carbazole derivates 株式会社半导体能源研究所 2018-09-21 CN disclosed
EP-3033405-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-05-09 EP disclosed
CN-107253929-A Carbazole derivates, and use light-emitting component, luminescent device and the electronic device of carbazole derivates 株式会社半导体能源研究所 2017-10-17 CN disclosed
CN-102391132-B Light-emitting element using spirofluorene derivative and electronic appliance SEMICONDUCTOR ENERGY LAB 2015-04-01 CN disclosed
CN-104447503-A Spirofluorene derivative, material for light-emitting element, light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LAB 2015-03-25 CN disclosed
CN-101952250-B Carbazole derivative, and light-emitting element, light-emitting device, and electronic device using carbazole derivative SEMICONDUCTOR ENERGY LAB 2014-11-26 CN disclosed
CN-103641726-A Spirofluorene derivative, material for light-emitting element, light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LAB 2014-03-19 CN disclosed
CN-103641770-A Spirofluorene derivative, material for light-emitting element, light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LAB 2014-03-19 CN disclosed
CN-101273008-A Spirofluorene derivative, material for light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LAB (JP) 2008-09-24 CN disclosed
CN-100357330-C Polar group-containing olefin copolymer, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS INC (JP) 2007-12-26 CN disclosed
CN-1737017-A Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS INC (JP) 2006-02-22 CN disclosed
CN-1737016-A Polar group-containing olefin copolymer, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS INC (JP) 2006-02-22 CN disclosed
CN-1219800-C Polar group-containing olefin copolymer, thermoplastic resin composition containing the same, and use thereof MITSUI CHEMICALS INC (JP) 2005-09-21 CN disclosed
CN-1399625-A Preparation of halogenated primary amines ALLIED SIGNAL INC (US) 2003-02-26 CN disclosed
CN-1342715-A Polar group-containing olefin copolymer, process for producing the same, thermoplastic resin composition containing the same, and use thereof MITSUI CHEMICALS INC (JP) 2002-04-03 CN disclosed
CN-1069659-C Conjugated polymers having spiro centers and their use as electroluminescence materials HOECHST AG (DE) 2001-08-15 CN disclosed
CN-1289468-A Use of spiro compound as laser dyes AXIVA GMBH (DE) 2001-03-28 CN disclosed
CN-1156728-A Olefin polymerization catalyst, process for preparing olefin polymer, and olefin polymer MITSUI PETROCHEMICAL IND (JP) 1997-08-13 CN disclosed
CN-1129714-A Conjugated polymers having spiro centers and their use as electroluminescence materials HOECHST AG (DE) 1996-08-28 CN disclosed
CN-1112951-A Spiro-compound and application as electric luminescent material HOECHST AG (DE) 1995-12-06 CN disclosed