SCHEMBL7184680

SCHEMBL7184680

CCOC(=O)N(c1ccccc1)c1ccc(C(=O)O)cc1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
NSD2 O96028 1/20 0.41
ESR1 P03372 1/20 0.41
APEX1 P27695 1/20 0.41
RECQL P46063 1/20 0.41
ESR2 Q92731 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 3/20 0.40
HSD17B10 Q99714 2/20 0.40
MAPT P10636 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40
CTDSP1 Q9GZU7 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7191598 0.93 HRH3 (0.39) ALDH1A1CTDSP1MEN1KMT2AHRH3
SCHEMBL7192752 0.90 ESR1 (0.43) POLBL3MBTL1ESR1ESR2TDP1
SCHEMBL7185632 0.87 POLB (0.40) POLBL3MBTL1NSD2ESR1APEX1
SCHEMBL7196469 0.87 ALDH1A1 (0.41) POLBL3MBTL1NSD2ESR1APEX1
SCHEMBL7187592 0.85 CTDSP1 (0.43) POLBL3MBTL1ALDH1A1HSD17B10MAPT
SCHEMBL7183167 0.85 TSHR (0.46) POLBL3MBTL1ALDH1A1HSD17B10MAPT
SCHEMBL7195265 0.81 HRH3 (0.37) KDM4EALDH1A1MEN1KMT2ALMNA
SCHEMBL1363531 0.78 L3MBTL1 (0.55) POLBL3MBTL1TDP1ALDH1A1HSD17B10
SCHEMBL7183116 0.78 ESR1 (0.41) POLBL3MBTL1ESR1ESR2TDP1
SCHEMBL31147823 0.76 L3MBTL1 (0.53) POLBL3MBTL1TDP1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 EP disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 POLB 3165/4885L3MBTL1 80/4885NSD2 2998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.