SCHEMBL7184769

SCHEMBL7184769

CC(C)OC(C)C.OC(c1ccccc1)(c1ccccc1)C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
ALOX15 P16050 1/20 0.41
CYP2D6 P10635 3/20 0.41
CYP2C19 P33261 3/20 0.41
HSD17B10 Q99714 1/20 0.41
CYP3A4 P08684 3/20 0.39
MAPK1 P28482 2/20 0.39
CYP1A2 P05177 2/20 0.39
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
KCNN4 O15554 2/20 0.38
CHRM2 P08172 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TTR P02766 1/20 0.36
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL2856857 0.80 KCNN4 (0.48) ALDH1A1ALOX15CYP2C19CYP3A4MAPK1
SCHEMBL7173455 0.80 CYP1A2 (0.48) ALDH1A1ALOX15CYP2D6CYP2C19HSD17B10
SCHEMBL36629 0.80 CYP1A2 (0.48) ALDH1A1ALOX15CYP2D6CYP2C19HSD17B10
SCHEMBL2857691 0.77 ALDH1A1 (0.42) ALDH1A1ALOX15CYP2D6CYP2C19HSD17B10
SCHEMBL7184767 0.77 CYP2D6 (0.38) ALDH1A1ALOX15CYP2D6CYP2C19HSD17B10
SCHEMBL982540 0.75 ALDH1A1 (0.42) ALDH1A1ALOX15CYP2D6CYP2C19HSD17B10
SCHEMBL30915208 0.75 IRAK4 (0.41) ALDH1A1CYP2D6CYP2C19HSD17B10CYP3A4
SCHEMBL2858368 0.74 L3MBTL1 (0.37) ALDH1A1ALOX15CYP2D6CYP2C19HSD17B10
Chlorobenzene SCHEMBL2958762 0.73 TSHR (0.58) ALDH1A1ALOX15CYP1A2MEN1KMT2A
Phenol SCHEMBL27265038 0.73 CA12 (0.58) ALDH1A1CYP3A4ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6545064-B1 Improved printability and other surface characteristics. AVERY DENNISON CORPORATION 2003-04-08 US disclosed
WO-2001038452-A1 COATING COMPOSITION AVERY DENNISON CORPORATION (US) 2001-05-31 WO disclosed
EP-0246918-B1 Curable prepolymers GRACE W R & CO (US) 1994-01-26 EP disclosed
EP-0219857-B1 STORAGE STABLE (METH)ACRYLATE PLASTISOLS W.R. Grace & Co.-Conn. (US) 1992-01-08 EP disclosed
EP-0406921-A2 Storage stable (meth) acrylate plastisols W.R. GRACE & CO. (US) 1991-01-09 EP disclosed
US-4857434-A Radiation curable liquid (meth) acrylated polymeric hydrocarbon maleate prepolymers and formulations containing same W. R. GRACE & CO. (US) 1989-08-15 US disclosed
EP-0287020-A2 Aqueous developable, curable composition of matter W.R. Grace & Co.-Conn. (US) 1988-10-19 EP disclosed
EP-0261890-A2 Radiation curable polymers W.R. Grace & Co.-Conn. (US) 1988-03-30 EP disclosed
EP-0246918-A1 Curable prepolymers W.R. Grace & Co.-Conn. (US) 1987-11-25 EP disclosed
EP-0240939-A2 Storage stable, heat curable, coating composition W.R. Grace & Co.-Conn. (US) 1987-10-14 EP disclosed
EP-0238863-A2 Uv or heat curable reinforced elastomer compositions W.R. Grace & Co.-Conn. (US) 1987-09-30 EP disclosed
US-4677179-A Storage stable, heat curable, coating composition W. R. GRACE (US) 1987-06-30 US disclosed
EP-0219857-A2 Storage stable (meth)acrylate plastisols W.R. Grace & Co.-Conn. (US) 1987-04-29 EP disclosed
US-4132812-A FREE RADICAL INITIATOR W. R. GRACE & CO. (US) 1979-01-02 US disclosed
US-4117017-A PROCESS FOR PREPARATION OF THIOLS USING A BENZOPINACOL INITIATOR W. R. GRACE & CO. (US) 1978-09-26 US disclosed
US-4117196-A PHOTOCURABLE IMIDIZABLE POLYENE-POLYTHIOL COMPOSITIONS W. R. GRACE & CO. (US) 1978-09-26 US disclosed
US-4080484-A POLYAMIDE-ACID OR POLYIMIDE W. R. GRACE & CO. (US) 1978-03-21 US disclosed
US-4020233-A Heat activated ethylenically unsaturated-polythiol compositions W. R. GRACE & CO. (US) 1977-04-26 US disclosed