Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13822511 | 0.84 | — | — | |
| SCHEMBL5911087 | 0.82 | KMT2A (0.39) | HTTALDH1A1KMT2ARAB9ALMNA | |
| SCHEMBL540785 | 0.79 | HTT (0.39) | HTTALDH1A1KMT2ARAB9ALMNA | |
| SCHEMBL10409485 | 0.76 | ALDH1A1 (0.54) | ALDH1A1RAB9ALMNAHPGDTSHR | |
| SCHEMBL8670292 | 0.74 | TSHR (0.40) | HTTALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL15732428 | 0.74 | ALDH1A1 (0.45) | HTTALDH1A1KMT2ARAB9ALMNA | |
| SCHEMBL3670816 | 0.74 | ALDH1A1 (0.38) | HTTALDH1A1KMT2ARAB9ALMNA | |
| SCHEMBL12881027 | 0.74 | HTT (0.39) | HTTALDH1A1KMT2ARAB9ALMNA | |
| SCHEMBL3929786 | 0.74 | ALDH1A1 (0.38) | HTTALDH1A1KMT2ARAB9ALMNA | |
| SCHEMBL8939923 | 0.72 | ALDH1A1 (0.47) | HTTALDH1A1KMT2ARAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1290056-A1 | POLYURETHANE COMPOSITIONS BASED ON POLYESTER BLOCK COPOLYMERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-03-12 | — | — | EP | disclosed |
| EP-1250394-A1 | POLYURETHANE COMPOSITIONS ON THE BASIS OF POLYESTER-POLYETHER COPOLYMERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001096436-A1 | POLYURETHANE COMPOSITIONS BASED ON POLYESTER BLOCK COPOLYMERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-20 | — | — | WO | disclosed |
| WO-2001046330-A1 | POLYURETHANE COMPOSITIONS ON THE BASIS OF POLYESTER-POLYETHER COPOLYMERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-06-28 | — | — | WO | disclosed |