Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 4/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7185565 | 1.00 | GRIK1 (0.50) | GRIK1PTGESALOX5PPARGCHRM1 | |
| SCHEMBL7182950 | 0.94 | PTGES (0.52) | GRIK1PTGESALOX5PPARGEPHX2 | |
| SCHEMBL7182944 | 0.94 | PTGES (0.52) | GRIK1PTGESALOX5PPARGEPHX2 | |
| SCHEMBL7175346 | 0.90 | GRIK1 (0.51) | GRIK1PTGESALOX5PPARGCYP1A2 | |
| SCHEMBL7175350 | 0.90 | GRIK1 (0.51) | GRIK1PTGESALOX5PPARGCYP1A2 | |
| SCHEMBL1861360 | 0.88 | GRIK1 (0.62) | GRIK1PTGESALOX5PPARGCHRM1 | |
| SCHEMBL5510828 | 0.86 | GRIK1 (0.56) | GRIK1PTGESALOX5PPARGCHRM1 | |
| SCHEMBL28380919 | 0.83 | EPHX2 (0.54) | PTGESALOX5PPARGEPHX2MMP2 | |
| SCHEMBL1131425 | 0.82 | GRIK1 (0.62) | GRIK1PTGESALOX5PPARGFOLH1 | |
| SCHEMBL1869110 | 0.81 | HDAC1 (0.59) | GRIK1PTGESALOX5PPARGCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1241941-B1 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | UNIV NORTH CAROLINA STATE (US) | 2003-06-18 | — | — | EP | claimed |