Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1857365 | 0.90 | CYP1A2 (0.61) | CYP1A2GRIK1CPA3LAP3ERAP2 | |
| SCHEMBL473644 | 0.89 | MMP2 (0.61) | MMP2MMP3GRIK1PTGESALOX5 | |
| SCHEMBL1861360 | 0.89 | GRIK1 (0.62) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| Water SCHEMBL4010621 | 0.88 | CYP1A2 (0.59) | CYP1A2GRIK1CPA3LAP3ERAP2 | |
| SCHEMBL5510828 | 0.88 | GRIK1 (0.56) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| SCHEMBL8904812 | 0.88 | MMP2 (0.56) | CYP1A2MMP2MMP3GRIK1PTGES | |
| SCHEMBL585398 | 0.87 | CYP1A2 (0.59) | CYP1A2MMP2MMP3GRIK1TSHR | |
| SCHEMBL1716640 | 0.86 | MMP2 (0.55) | MMP2MMP3GRIK1PTGESALOX5 | |
| SCHEMBL7077500 | 0.86 | MMP2 (0.55) | MMP2MMP3GRIK1PTGESALOX5 | |
| SCHEMBL8905851 | 0.86 | MMP2 (0.55) | MMP2MMP3GRIK1PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105544-A1 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2011-05-05 | — | — | US | claimed |
| WO-2009080722-A2 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2009-07-02 | — | — | WO | claimed |
| CN-101370467-A | Solubilizing agents for active or functional organic compounds | ISP INVESTMENTS INC (US) | 2009-02-18 | — | — | CN | claimed |
| CN-1100408-A | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1995-03-22 | — | — | CN | claimed |
| EP-3360175-B1 | FORMULATIONS COMPRISING AT LEAST TWO ORGANIC SEMICONDUCTING COMPOUNDS AND AT LEAST TWO SOLVENTS | MERCK PATENT GMBH (DE) | 2023-05-17 | — | — | EP | disclosed |
| US-11427700-B2 | Method of manufacturing rubber composition | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2022-08-30 | — | — | US | disclosed |
| US-10686132-B2 | Formulations comprising organic at least two semiconducting compounds and at least two solvents | MERCK PATENT GMBH (DE) | 2020-06-16 | — | — | US | disclosed |
| EP-3636807-A1 | CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 2020-04-15 | — | — | EP | disclosed |
| US-20200095217-A1 | HYDROXY FORMAMIDE DERIVATIVES AND THEIR USE | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2020-03-26 | — | — | US | disclosed |
| US-10450288-B2 | Hydroxy formamide derivatives and their use | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED (GB) | 2019-10-22 | — | — | US | disclosed |
| US-20190115536-A1 | FORMULATIONS COMPRISING ORGANIC AT LEAST TWO SEMICONDUCTING COMPOUNDS AND AT LEAST TWO SOLVENTS | MERCK PATENT GMBH (DE) | 2019-04-18 | — | — | US | disclosed |
| CN-108367178-A | Has the composition of stable taste and smell | 西姆莱斯股份公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-101370467-A | Solubilizing agents for active or functional organic compounds | ISP INVESTMENTS INC (US) | 2009-02-18 | — | — | CN | disclosed |
| EP-1986589-A2 | SOLUBILIZING AGENTS FOR ACTIVE OR FUNCTIONAL ORGANIC COMPOUNDS | ISP INVESTMENTS INC. (US) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007087278-A2 | SOLUBILIZING AGENTS FOR ACTIVE OR FUNCTIONAL ORGANIC COMPOUNDS | ISP INVESTMENTS INC (US) | 2007-08-02 | — | — | WO | disclosed |
| US-20070172437-A1 | Solubilizing agents for active or functional organic compounds | ISP INVESTMENTS INC. | 2007-07-26 | — | — | US | disclosed |
| CN-1090186-C | HIV protease inhibitors in pharmaceutical combinations for the treatment of AIDS | MERCK & CO INC (US) | 2002-09-04 | — | — | CN | disclosed |
| CN-1176250-A | HIV protease inhibitors useful for treatment of AIDS | MERCK & CO INC (US) | 1998-03-18 | — | — | CN | disclosed |
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| US-4523912-A | Mineral tooth with silane-coupled adhesive plastic part | VEB KOMBINAT MEDIZIN-UND LABORTECHNIK LEIPZIG (DD) | 1985-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200095217-A1 | HYDROXY FORMAMIDE DERIVATIVES AND THEIR USE | BMP1, BMPR1A, BMPR2 | HDAC1 243/4885HDAC2 1165/4885CHRM1 1980/4885 |
| US-10450288-B2 | Hydroxy formamide derivatives and their use | BMP1, BMPR1A, BMPR2 | HDAC1 243/4885HDAC2 1165/4885CHRM1 1980/4885 |
| US-20110105544-A1 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | AKR1C3, TPD52L2, HCCS | HDAC1 1153/4885HDAC2 1328/4885CHRM1 151/4885 |
| US-20070172437-A1 | Solubilizing agents for active or functional organic compounds | CEL, PIGO, ERG28 | HDAC1 172/4885HDAC2 417/4885CHRM1 1390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.