Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 4/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.52 |
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7182944 | 1.00 | PTGES (0.52) | PTGESALOX5PPARGGRIK1MMP2 | |
| SCHEMBL7185562 | 0.94 | GRIK1 (0.50) | PTGESALOX5PPARGGRIK1MMP2 | |
| SCHEMBL7185565 | 0.94 | GRIK1 (0.50) | PTGESALOX5PPARGGRIK1MMP2 | |
| SCHEMBL7175346 | 0.90 | GRIK1 (0.51) | PTGESALOX5PPARGGRIK1MMP2 | |
| SCHEMBL7175350 | 0.90 | GRIK1 (0.51) | PTGESALOX5PPARGGRIK1MMP2 | |
| SCHEMBL1131425 | 0.88 | GRIK1 (0.62) | PTGESALOX5PPARGGRIK1MMP2 | |
| SCHEMBL28380919 | 0.86 | EPHX2 (0.54) | PTGESALOX5PPARGMMP2MMP3 | |
| SCHEMBL8845789 | 0.85 | PTGES (0.56) | PTGESALOX5PPARGGRIK1MMP2 | |
| SCHEMBL8845872 | 0.85 | PTGES (0.56) | PTGESALOX5PPARGGRIK1MMP2 | |
| SCHEMBL473644 | 0.85 | MMP2 (0.61) | PTGESALOX5PPARGGRIK1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1241941-B1 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | UNIV NORTH CAROLINA STATE (US) | 2003-06-18 | — | — | EP | claimed |