Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PTGES | O14684 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7175350 | 1.00 | GRIK1 (0.51) | GRIK1CYP1A2CA2MAPK1PPARG | |
| SCHEMBL7182950 | 0.90 | PTGES (0.52) | GRIK1CYP1A2CA2MAPK1PPARG | |
| SCHEMBL7185562 | 0.90 | GRIK1 (0.50) | GRIK1CYP1A2PPARGPTGESALOX5 | |
| SCHEMBL7182944 | 0.90 | PTGES (0.52) | GRIK1CYP1A2CA2MAPK1PPARG | |
| SCHEMBL7185565 | 0.90 | GRIK1 (0.50) | GRIK1CYP1A2PPARGPTGESALOX5 | |
| SCHEMBL1026190 | 0.88 | GRIK1 (0.64) | GRIK1CYP1A2CA2MAPK1PPARG | |
| SCHEMBL586255 | 0.86 | GRIK1 (0.58) | GRIK1CYP1A2CA2MAPK1PPARG | |
| SCHEMBL29650381 | 0.84 | GRIK1 (0.56) | GRIK1CYP1A2CA2MAPK1PPARG | |
| SCHEMBL11050992 | 0.84 | GRIK1 (0.56) | GRIK1CYP1A2CA2MAPK1PPARG | |
| SCHEMBL7175234 | 0.82 | LTB4R (0.52) | GRIK1MAPK1TOP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1241941-B1 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | UNIV NORTH CAROLINA STATE (US) | 2003-06-18 | — | — | EP | claimed |