Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 8/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL305329 | 0.73 | ALDH1A1 (0.49) | GPR35ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL31220465 | 0.73 | ALDH1A1 (0.49) | GPR35ALDH1A1TSHRCYP3A4PPIA | |
| SCHEMBL304867 | 0.73 | ALDH1A1 (0.49) | GPR35ALDH1A1TSHRCYP3A4PPIA | |
| SCHEMBL23144771 | 0.72 | GPR35 (0.56) | GPR35ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL27488360 | 0.72 | GPR35 (0.56) | PDE7AGPR35ALDH1A1MAPTLMNA | |
| SCHEMBL13401628 | 0.71 | GPR35 (0.51) | PDE7AGPR35ALDH1A1MAPTPDE7B | |
| SCHEMBL4284955 | 0.70 | PDE7A (0.50) | PDE7AALDH1A1MAPTPDE7BLMNA | |
| SCHEMBL21625 | 0.70 | MAPT (0.42) | PDE7AGPR35ALDH1A1MAPTPDE7B | |
| SCHEMBL772624 | 0.69 | CYP1A2 (0.48) | GPR35ALDH1A1MAPTHTTNPSR1 | |
| SCHEMBL20727289 | 0.69 | PDE7A (0.55) | PDE7AGPR35ALDH1A1MAPTPDE7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007955-A2 | BIPHENYL APURINIC/APYRIMIDINIC SITE ENDONUCLEASE INHIBITORS TO TREAT CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-01-30 | — | — | WO | claimed |