Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31220465 | 1.00 | ALDH1A1 (0.49) | ALDH1A1CYP3A4GPR35MAPK1TSHR | |
| SCHEMBL305329 | 0.92 | ALDH1A1 (0.49) | ALDH1A1CYP3A4GPR35MAPK1TSHR | |
| SCHEMBL810599 | 0.85 | ALDH1A1 (0.58) | ALDH1A1CYP3A4GPR35MAPK1TSHR | |
| SCHEMBL62337 | 0.84 | GPR35 (0.54) | ALDH1A1GPR35MAPK1TSHRTP53 | |
| SCHEMBL772624 | 0.84 | CYP1A2 (0.48) | ALDH1A1CYP3A4GPR35MAPK1TSHR | |
| SCHEMBL305109 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP3A4GPR35MAPK1TSHR | |
| SCHEMBL864500 | 0.82 | TSHR (0.50) | ALDH1A1CYP3A4MAPK1TSHRPPIA | |
| SCHEMBL29586844 | 0.82 | PPIA (0.47) | ALDH1A1CYP3A4GPR35MAPK1TSHR | |
| SCHEMBL80032 | 0.82 | PPIA (0.47) | ALDH1A1CYP3A4GPR35MAPK1TSHR | |
| SCHEMBL29721556 | 0.82 | TSHR (0.50) | ALDH1A1CYP3A4MAPK1TSHRPPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260022122-A1 | NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME | CHECKMATE THERAPEUTICS INC. (KR) | 2026-01-22 | — | — | US | disclosed |
| WO-2023229346-A1 | NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME | 주식회사 체크메이트테라퓨틱스 | 2023-11-30 | — | — | WO | disclosed |
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | DISCUVA LTD. (GB) | 2019-06-27 | — | — | US | disclosed |
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | DISCUVA LTD. (GB) | 2019-06-27 | — | — | US | disclosed |
| US-20130190271-A1 | FUSED HETEROCYCLIC COMPOUNDS AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-25 | — | — | US | disclosed |
| US-8445522-B2 | Substituted 2-(4-pyridyl)benzoxazoles, and compositions thereof, for use in arthropod pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-21 | — | — | US | disclosed |
| US-8324387-B2 | Substituted Oxazolo[5,4-b]pyridines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20120264750-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-18 | — | — | US | disclosed |
| US-20120252804-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120252803-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | US | disclosed |
| WO-2008039418-A2 | ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2008-04-03 | — | — | WO | disclosed |
| WO-2008039418-A2 | ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2008-04-03 | — | — | WO | disclosed |
| CN-101151259-A | Heteroaryl urea derivatives useful for inhibition of CHKI | ICOS CORP (US) | 2008-03-26 | — | — | CN | disclosed |
| EP-1869020-A1 | HETEROARYL UREA DERIVATIVES USEFUL FOR INHIBITING CHKl | ICOS Corporation (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006105262-A1 | HETEROARYL UREA DERIVATIVES USEFUL FOR INHIBITING CHKl | ICOS CORPORATION (US) | 2006-10-05 | — | — | WO | disclosed |
| US-4593109-A | Miticidal 1-(2-alkyl-2,3-dihydrobenzofuran-7-yl)-4-alkoxy-4-alkylsemicarbazides | SHELL OIL COMPANY (US) | 1986-06-03 | — | — | US | disclosed |
| US-4587259-A | Miticidal 2-(2-methyl-2,3-dihydro-benzofuran-7-yl)hydrazinecarboxylic acid esters | SHELL OIL COMPANY (US) | 1986-05-06 | — | — | US | disclosed |
| US-4577011-A | Miticidal 2-(2-alkyl-2,3-dihydrobenzofuran-7-yl)-N-alkoxy-N-alkyl-diazenecarboxamides | SHELL OIL COMPANY (US) | 1986-03-18 | — | — | US | disclosed |
| US-4558040-A | Miticidal (2-alkyl-3,4-dihydro-2H-1-benzopyran-8-yl)-diazenecarboxylic acid esters | SHELL OIL COMPANY (US) | 1985-12-10 | — | — | US | disclosed |
| US-4550121-A | AGRICULTURE | SHELL OIL COMPANY (US) | 1985-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264750-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | DDT, ACHE, AADAC | ALDH1A1 2877/4885CYP3A4 2614/4885GPR35 3737/4885 |
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | B3GNT2, RPN2, RPN1 | ALDH1A1 3333/4885CYP3A4 2095/4885GPR35 1158/4885 |
| US-20130190271-A1 | FUSED HETEROCYCLIC COMPOUNDS AND USES THEREOF | CYC1, C9, C5 | ALDH1A1 620/4885CYP3A4 308/4885GPR35 3572/4885 |
| US-20120252803-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | DDT, ACHE, AADAC | ALDH1A1 3770/4885CYP3A4 357/4885GPR35 2440/4885 |
| US-20120252804-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | DDT, AADAC, CYP4F3 | ALDH1A1 1829/4885CYP3A4 256/4885GPR35 2487/4885 |
| US-20260022122-A1 | NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME | NAMPT, NAPRT, NNT | ALDH1A1 789/4885CYP3A4 1175/4885GPR35 2281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.