Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304867 | 0.92 | ALDH1A1 (0.49) | ALDH1A1CYP3A4GPR35PPIAMAPK1 | |
| SCHEMBL31220465 | 0.92 | ALDH1A1 (0.49) | ALDH1A1CYP3A4GPR35PPIAMAPK1 | |
| SCHEMBL6156287 | 0.85 | ALDH1A1 (0.49) | ALDH1A1CYP3A4GPR35PPIAMAPK1 | |
| SCHEMBL62337 | 0.84 | GPR35 (0.54) | ALDH1A1GPR35MAPK1TSHRTP53 | |
| SCHEMBL305109 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP3A4GPR35MAPK1TSHR | |
| SCHEMBL772624 | 0.84 | CYP1A2 (0.48) | ALDH1A1CYP3A4GPR35PPIAMAPK1 | |
| SCHEMBL5068830 | 0.82 | PPIA (0.47) | ALDH1A1CYP3A4GPR35PPIAMAPK1 | |
| SCHEMBL29664349 | 0.82 | GPR35 (0.52) | ALDH1A1CYP3A4GPR35MAPK1TSHR | |
| SCHEMBL8580180 | 0.82 | GPR35 (0.52) | ALDH1A1CYP3A4GPR35MAPK1TSHR | |
| SCHEMBL1626324 | 0.82 | TSHR (0.50) | ALDH1A1CYP3A4GPR35PPIAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12459906-B2 | 3-(5-chloro-2-oxobenzo[d]oxazol-3(2H)-yl) propanoic acid derivatives as KMO inhibitors | DR. FALK PHARMA GMBH (DE) | 2025-11-04 | — | — | US | disclosed |
| EP-4623914-A1 | USE OF 8-HYDROXYQUINOLINE DERIVATIVE | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2025-10-01 | — | — | EP | disclosed |
| US-12391663-B2 | Isoindolinone compounds | MONTE ROSA THERAPEUTICS AG (CH) | 2025-08-19 | — | — | US | disclosed |
| CN-120035438-A | Use of 8-hydroxyquinoline derivatives | 江苏亚虹医药科技股份有限公司 | 2025-05-23 | — | — | CN | disclosed |
| US-20250034110-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. | 2025-01-30 | — | — | US | disclosed |
| CN-118525018-A | Bialkyne compound and application thereof | 上海艾力斯医药科技股份有限公司 | 2024-08-20 | — | — | CN | disclosed |
| US-20240261274-A1 | TREATMENT OF MYC-DRIVEN CANCERS WITH GSPT1 DEGRADERS | MONTE ROSA THERAPEUTICS AG (CH) | 2024-08-08 | — | — | US | disclosed |
| US-20240246916-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVES, PREPARATION METHOD THEREFORE AND MEDICAL USE THEREOF | JIANGSU YAHONG MEDITECH CO., LTD. (CN) | 2024-07-25 | — | — | US | disclosed |
| US-20240216355-A1 | PHARMACEUTICAL COMPOSITIONS FOR USE IN THE PREVENTION AND TREATMENT OF A DISEASE OR DISORDER CAUSED BY OR ASSOCIATED WITH ONE OR MORE PREMATURE TERMINATION CODONS | MONTE ROSA THERAPEUTICS AG (CH) | 2024-07-04 | — | — | US | disclosed |
| EP-4380560-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Contineum Therapeutics, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| CN-1332725-A | Thiourea inhibitors of herpes viruses | AMERICAN HOME PROD (US) | 2002-01-23 | — | — | CN | disclosed |
| CN-1329608-A | Alpha-methylbenzyl-containing thioure a inhibitors of herpes viruses containing phenylenediamine group | AMERICAN HOME PROD (US) | 2002-01-02 | — | — | CN | disclosed |
| EP-1039876-A1 | DIRECT HAIR DYE COMPOSITIONS AND METHODS CONTAINING NOVEL ANTHRAQUINONE MIXTURES | Bristol-Myers Squibb Company (US) | 2000-10-04 | — | — | EP | disclosed |
| CN-1262612-A | Direct hair dye compositions containing anthraquinone mixtures and method thereof | BRISTOL MYERS SQUIBB CO (US) | 2000-08-09 | — | — | CN | disclosed |
| US-5961664-A | THREE 1,4-HYDROXYALKYLAMINO-ANTHRAQUINONE DERIVATIVES, WHEREIN TWO OF THE ANTHRAQUINONE COMPOUNDS IN THE MIXTURE ARE SYMMETRIC AND THE OTHER ANTHRAQUINONE COMPOUND IS ASYMMETRIC, AND WHEREIN EACH OF THE ANTHRAQUINONE COMPOUNDS HAS SIMILAR | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-10-05 | — | — | US | disclosed |
| WO-1999002124-A2 | DIRECT HAIR DYE COMPOSITIONS AND METHODS CONTAINING NOVEL ANTHRAQUINONE MIXTURES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-21 | — | — | WO | disclosed |
| US-5334225-A | Imparts color tone of high chroma; excellent in coloring power and fastness | KAO CORPORATION (JP) | 1994-08-02 | — | — | US | disclosed |
| EP-0579204-A2 | Dye composition for a keratinous fiber | KAO CORPORATION (JP) | 1994-01-19 | — | — | EP | disclosed |
| US-4587259-A | Miticidal 2-(2-methyl-2,3-dihydro-benzofuran-7-yl)hydrazinecarboxylic acid esters | SHELL OIL COMPANY (US) | 1986-05-06 | — | — | US | disclosed |
| US-4207318-A | ANTIALLERGIC ACTIVITY, BRONCHODILATOR | ROUSSEL UCLAF (FR) | 1980-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12391663-B2 | Isoindolinone compounds | CYP4F2, AOC2, AOC3 | ALDH1A1 1142/4885CYP3A4 684/4885GPR35 3797/4885 |
| US-20240216355-A1 | PHARMACEUTICAL COMPOSITIONS FOR USE IN THE PREVENTION AND TREATMENT OF A DISEASE OR DISORDER CAUSED BY OR ASSOCIATED WITH ONE OR MORE PREMATURE TERMINATION CODONS | UPF1, NSUN2, RTF2 | ALDH1A1 4150/4885CYP3A4 3128/4885GPR35 4234/4885 |
| US-20240246916-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVES, PREPARATION METHOD THEREFORE AND MEDICAL USE THEREOF | CYP3A7, UGT1A7, UGT2B7 | ALDH1A1 1017/4885CYP3A4 62/4885GPR35 1965/4885 |
| US-20250034110-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | LPAR1, LPAR2, LPAR3 | ALDH1A1 1523/4885CYP3A4 4412/4885GPR35 292/4885 |
| US-20240261274-A1 | TREATMENT OF MYC-DRIVEN CANCERS WITH GSPT1 DEGRADERS | MYC, MYCBP, GSPT1 | ALDH1A1 4276/4885CYP3A4 4304/4885GPR35 2597/4885 |
| US-12459906-B2 | 3-(5-chloro-2-oxobenzo[d]oxazol-3(2H)-yl) propanoic acid derivatives as KMO inhibitors | KMO, AMY1A, AMY2A | ALDH1A1 1994/4885CYP3A4 3702/4885GPR35 1733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.