Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8974969 | 0.77 | AKR1C3 (0.53) | ALDH1A1AKR1C3SLC16A3MRGPRX4LMNA | |
| SCHEMBL7188480 | 0.75 | MRGPRX4 (0.55) | ALDH1A1AKR1C3KDM4EHPGDHTT | |
| SCHEMBL18392260 | 0.74 | MCL1 (0.70) | ALDH1A1LMNA | |
| SCHEMBL30076572 | 0.74 | MCL1 (0.70) | ALDH1A1LMNA | |
| SCHEMBL3872842 | 0.72 | POLB (0.53) | ALDH1A1AKR1C3HTTSLC16A3MRGPRX4 | |
| SCHEMBL5928513 | 0.72 | AKR1C3 (0.47) | ALDH1A1AKR1C3SLC16A3MRGPRX4LMNA | |
| SCHEMBL7826055 | 0.70 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDHTTGAA | |
| SCHEMBL1574123 | 0.70 | PPARA (0.50) | ALDH1A1HPGDLMNAPPARA | |
| SCHEMBL5004759 | 0.70 | PPARA (0.48) | ALDH1A1HPGDPPARA | |
| SCHEMBL5287179 | 0.70 | PPARA (0.45) | ALDH1A1NPC1RAB9APPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586256-B1 | Analyte-binding and reporter moieties covalently attached to a framework including two trityl groups connected by a linear spacer such as ethyne or butadiyne; fluorescent signal | THE PENN STATE RESEARCH FOUNDATION | 2003-07-01 | — | — | US | disclosed |