Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311403 | 0.78 | AKR1C3 (0.85) | AKR1C3ALDH1A1SLC16A3POLBMAPT | |
| SCHEMBL31480233 | 0.76 | AKR1C3 (0.55) | AKR1C3ALDH1A1HTTCA12CA1 | |
| SCHEMBL7186113 | 0.75 | ALDH1A1 (0.47) | MRGPRX4AKR1C3ALDH1A1HTTKDM4E | |
| SCHEMBL7076834 | 0.74 | ALDH1A1 (0.65) | MRGPRX4AKR1C3ALDH1A1HPGDMAPT | |
| SCHEMBL3552787 | 0.71 | SLC16A3 (0.74) | MRGPRX4AKR1C3ALDH1A1HTTSLC16A3 | |
| SCHEMBL7826055 | 0.71 | ALDH1A1 (0.68) | ALDH1A1HTTKDM4EHPGD | |
| SCHEMBL22480946 | 0.71 | MRGPRX4 (1.00) | MRGPRX4AKR1C3HTTKDM4ESLC16A3 | |
| SCHEMBL27635203 | 0.71 | AKR1C3 (0.63) | AKR1C3NPC1RAB9A | |
| SCHEMBL8974969 | 0.70 | AKR1C3 (0.53) | MRGPRX4AKR1C3ALDH1A1SLC16A3POLB | |
| SCHEMBL28395459 | 0.70 | RECQL (0.62) | ALDH1A1HTTKDM4EHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586256-B1 | Analyte-binding and reporter moieties covalently attached to a framework including two trityl groups connected by a linear spacer such as ethyne or butadiyne; fluorescent signal | THE PENN STATE RESEARCH FOUNDATION | 2003-07-01 | — | — | US | disclosed |