Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | PDE9A | O76083 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456189 | 0.91 | B3GNT2 (0.43) | ALDH1A1HSP90AA1MEN1CYP1A2CYP3A4 | |
| SCHEMBL7185230 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HSP90AA1MEN1CYP1A2CYP3A4 | |
| SCHEMBL7183756 | 0.80 | PDE4B (0.47) | MEN1KMT2APOLBB3GNT2 | |
| SCHEMBL7178509 | 0.80 | PGR (0.38) | MAPTPOLB | |
| SCHEMBL7187351 | 0.80 | PGR (0.38) | MAPTPOLB | |
| SCHEMBL7178381 | 0.79 | ALDH1A1 (0.69) | ALDH1A1HSP90AA1MEN1CYP1A2CYP3A4 | |
| SCHEMBL7184199 | 0.77 | MEN1 (0.47) | ALDH1A1HSP90AA1MEN1CYP1A2CYP3A4 | |
| SCHEMBL7183793 | 0.76 | HSP90AA1 (0.46) | ALDH1A1HSP90AA1MEN1CYP1A2CYP3A4 | |
| SCHEMBL7452685 | 0.73 | B3GNT2 (0.45) | ALDH1A1HSP90AA1MEN1CYP1A2CYP3A4 | |
| SCHEMBL7183924 | 0.72 | MEN1 (0.42) | ALDH1A1HSP90AA1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6582351-B1 | Benzimidazole heterocyclic compounds having pharmacological activities, and their use as a medicament for treatment or prevention of diseases mediated by cGMP-PDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-24 | — | — | US | disclosed |