Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 5/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | PPID | Q08752 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202116 | 0.90 | SYK (0.40) | CKS1BSKP1SKP2SYKIDO1 | |
| SCHEMBL16490057 | 0.75 | SYK (0.49) | CKS1BSKP1SKP2SYKIDO1 | |
| SCHEMBL14196595 | 0.75 | SYK (0.49) | CKS1BSKP1SKP2SYKIDO1 | |
| SCHEMBL6046941 | 0.75 | HPGD (0.41) | SYKIDO1CTSSCTSLCTSB | |
| SCHEMBL10077228 | 0.73 | SYK (0.36) | CKS1BSKP1SKP2SYKMAPT | |
| SCHEMBL3670409 | 0.73 | RAB9A (0.47) | CKS1BSKP1SKP2SYKIDO1 | |
| SCHEMBL23453049 | 0.73 | TDP1 (0.41) | CKS1BSKP1SKP2 | |
| SCHEMBL460716 | 0.73 | MAPT (0.36) | CKS1BSKP1SKP2SYKBRD4 | |
| SCHEMBL7717128 | 0.72 | ABL1 (0.40) | CKS1BSKP1SKP2MAPTSIGMAR1 | |
| SCHEMBL432254 | 0.72 | CCNE2 (0.40) | BRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105286-A1 | Linked peptide nucleic acids | EGHOLM MICHAEL (US) | 2003-06-05 | — | — | US | disclosed |
| US-6451968-B1 | HOOGSTEEN TYPE BASE PAIRING IN TRIPLEX MOTIF; DIAGNOSIS; HEAT RESISTANCE; DETECTION OF POINT MUTATIONS, RESTRICTION ENZYME SITES, AND TRANSCRIPTION INHIBITION | ISIS PHARMACEUTICALS, INC. | 2002-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105286-A1 | Linked peptide nucleic acids | RNGTT, NT5C3B, DPYD | CKS1B 1294/4885SKP1 4276/4885SKP2 2623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.