Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045923 | 0.88 | KMT2A (0.46) | MEN1KMT2ARAB9APTGESHPGD | |
| SCHEMBL7045443 | 0.88 | MEN1 (0.45) | MEN1KMT2ARAB9AEPHX2HPGD | |
| SCHEMBL7042908 | 0.85 | DAGLA (0.47) | MEN1KMT2ARAB9AHPGDASAH1 | |
| SCHEMBL27563540 | 0.82 | PTGES (0.38) | MEN1KMT2APTGESHPGDCSNK1D | |
| SCHEMBL6463984 | 0.77 | DAGLA (0.40) | RAB9AKDM4EASAH1 | |
| SCHEMBL7049339 | 0.77 | CTSS (0.53) | MEN1KMT2ARAB9APTGESEPHX2 | |
| SCHEMBL7049306 | 0.76 | DAGLA (0.44) | MEN1KMT2ARAB9AHPGDKDM4E | |
| SCHEMBL7186564 | 0.76 | MMP1 (0.39) | MEN1KMT2ARAB9APTGESEPHX2 | |
| SCHEMBL7047959 | 0.75 | MEN1 (0.44) | MEN1KMT2ARAB9AEPHX2HPGD | |
| SCHEMBL7049340 | 0.74 | MEN1 (0.39) | MEN1KMT2ARAB9APTGESHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |