Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466103 | 0.83 | DAGLA (0.56) | DAGLAASAH1FAAHNPC1RAB9A | |
| SCHEMBL7186569 | 0.77 | MEN1 (0.40) | ASAH1RAB9AKDM4E | |
| SCHEMBL6466216 | 0.74 | DAGLA (0.44) | DAGLAPIM1PIM2ASAH1AKR1B1 | |
| SCHEMBL6463980 | 0.73 | PIM1 (0.38) | DAGLAPIM1PIM2ASAH1AKR1B1 | |
| SCHEMBL6466221 | 0.69 | DAGLA (0.41) | DAGLAPIM1PIM2AKR1B1PPARG | |
| SCHEMBL6466213 | 0.67 | CTSL (0.45) | DAGLAPIM1PIM2ASAH1AKR1B1 | |
| SCHEMBL7049306 | 0.67 | DAGLA (0.44) | DAGLAFAAHCES1HDAC2HDAC8 | |
| SCHEMBL15899682 | 0.66 | S1PR1 (0.59) | PPARGS1PR1HDAC3HDAC1HDAC2 | |
| SCHEMBL6466340 | 0.65 | LMNA (0.39) | DAGLAPPARGPPARAFAAHCES1 | |
| SCHEMBL3639187 | 0.64 | PIM1 (0.55) | DAGLAPIM1PIM2AKR1B1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |