Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047980 | 0.93 | TBXA2R (0.37) | MEN1KMT2APRSS1PRSS2PRSS3 | |
| SCHEMBL7044845 | 0.89 | KCNA5 (0.39) | KCNA5L3MBTL1ALDH1A1HPGDSLC1A3 | |
| SCHEMBL7049037 | 0.89 | KCNA5 (0.39) | KCNA5L3MBTL1ALDH1A1SLC1A3SLC1A1 | |
| SCHEMBL7046299 | 0.88 | L3MBTL1 (0.44) | KMT2AKCNA5L3MBTL1ALDH1A1HPGD | |
| SCHEMBL7049297 | 0.87 | HPGD (0.40) | MEN1KMT2AKCNA5ALDH1A1HPGD | |
| SCHEMBL7045334 | 0.86 | CYP1A2 (0.42) | KMT2AKCNA5L3MBTL1NR3C2ALDH1A1 | |
| SCHEMBL7047185 | 0.82 | CTSL (0.37) | ALDH1A1SLC1A3SLC1A1 | |
| SCHEMBL7049752 | 0.80 | KMT2A (0.43) | MEN1KMT2AL3MBTL1SLC1A3SLC1A1 | |
| SCHEMBL7185049 | 0.80 | MEN1 (0.35) | CACNA1HMEN1KMT2AHCRTR1PRSS1 | |
| SCHEMBL7183275 | 0.78 | MEN1 (0.38) | MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |