Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 2/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046968 | 0.90 | ELANE (0.44) | LMNAL3MBTL1XDHELANESMN1; SMN2 | |
| SCHEMBL6464575 | 0.89 | LMNA (0.44) | KMT2ALMNACETPXDHCASP3 | |
| SCHEMBL7045499 | 0.85 | ELANE (0.43) | XDHELANESLC1A3SLC1A1MAPT | |
| SCHEMBL7183396 | 0.81 | CTSS (0.44) | KMT2ALMNACASP3SMN1; SMN2FFAR2 | |
| SCHEMBL7049761 | 0.81 | ELANE (0.46) | LMNAL3MBTL1XDHELANESMN1; SMN2 | |
| SCHEMBL6063445 | 0.81 | PTGER4 (0.47) | KMT2ALMNAMEN1L3MBTL1TP53 | |
| SCHEMBL7186575 | 0.80 | CACNA1H (0.37) | KMT2ALMNAMEN1L3MBTL1SLC1A3 | |
| SCHEMBL7047980 | 0.80 | TBXA2R (0.37) | KMT2ALMNAMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7046461 | 0.79 | ELANE (0.43) | XDHELANESLC1A3SLC1A1ATM | |
| SCHEMBL7046917 | 0.79 | HDAC1 (0.40) | LMNAL3MBTL1SMN1; SMN2SLC1A3SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | SERPINB1, CTRL, CTSZ | KMT2A 3705/4885LMNA 1755/4885MEN1 4023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.