Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | MASP2 | O00187 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046903 | 0.93 | TBXA2R (0.35) | MEN1KMT2AL3MBTL1ALDH1A1KCNA5 | |
| SCHEMBL7045973 | 0.90 | PSMB5 (0.40) | L3MBTL1ALDH1A1HPGDKCNA5LMNA | |
| SCHEMBL7042863 | 0.90 | KCNA5 (0.37) | ALDH1A1MAPTKCNA5 | |
| SCHEMBL7042125 | 0.88 | L3MBTL1 (0.39) | KMT2AL3MBTL1ALDH1A1HPGDKCNA5 | |
| SCHEMBL7044814 | 0.88 | SGMS2 (0.37) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL7049145 | 0.87 | KCNA5 (0.38) | KMT2AL3MBTL1ALDH1A1HPGDMAPT | |
| SCHEMBL7046404 | 0.85 | MAPT (0.35) | L3MBTL1ALDH1A1MAPTKCNA5MAPK1 | |
| SCHEMBL7186575 | 0.80 | CACNA1H (0.37) | MEN1KMT2AHCRTR1L3MBTL1CACNA1H | |
| SCHEMBL7045323 | 0.79 | MGLL (0.36) | MEN1KMT2A | |
| SCHEMBL6465152 | 0.79 | MAPT (0.39) | MEN1KMT2AL3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |