Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.32 |
| ▸ | KDM4A | O75164 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | TET3 | O43151 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.31 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL7174561 | 0.88 | TSHR (0.45) | LMNAALDH1A1KDM4EDUSP3MEN1 | |
| SCHEMBL5888683 | 0.84 | LMNA (0.53) | LMNAEGLN1KDM2AALDH1A1KDM6B | |
| Bicarbonate SCHEMBL21084342 | 0.82 | LMNA (0.50) | LMNAEGLN1KDM2AALDH1A1KDM6B | |
| Succinic Acid SCHEMBL6854426 | 0.82 | LMNA (0.56) | LMNAEGLN1KDM2AALDH1A1KDM6B | |
| Succinic Acid SCHEMBL19478236 | 0.82 | LMNA (0.56) | LMNAEGLN1KDM2AALDH1A1KDM6B | |
| Succinic Acid SCHEMBL321511 | 0.82 | LMNA (0.56) | LMNAEGLN1KDM2AALDH1A1KDM6B | |
| Succinic Acid SCHEMBL29758477 | 0.82 | LMNA (0.56) | LMNAEGLN1KDM2AALDH1A1KDM6B | |
| Succinic Acid SCHEMBL7186939 | 0.79 | LMNA (0.53) | LMNAEGLN1KDM2AALDH1A1KDM6B | |
| Glycerin SCHEMBL7159292 | 0.79 | LMNA (0.53) | LMNAALDH1A1KDM4EDUSP3MEN1 | |
| Glycerin SCHEMBL1357013 | 0.79 | LMNA (0.53) | LMNAALDH1A1KDM4EDUSP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129120-B1 | MODIFIED POLYISOCYANATES | RHODIA CHIMIE SA (FR) | 2003-12-10 | — | — | EP | claimed |