Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.56 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.56 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.45 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.43 |
| ▸ | KDM4A | O75164 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | TET3 | O43151 | 1/20 | 0.43 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.43 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL321511 | 1.00 | LMNA (0.56) | LMNAEGLN1ALKBH5SUCNR1ALDH1A1 | |
| Succinic Acid SCHEMBL29758477 | 1.00 | LMNA (0.56) | LMNAEGLN1ALKBH5SUCNR1ALDH1A1 | |
| Succinic Acid SCHEMBL19478236 | 1.00 | LMNA (0.56) | LMNAEGLN1ALKBH5SUCNR1ALDH1A1 | |
| Succinic Acid SCHEMBL7186939 | 0.97 | LMNA (0.53) | LMNAEGLN1ALKBH5SUCNR1ALDH1A1 | |
| Succinic Acid SCHEMBL15323713 | 0.89 | LMNA (0.45) | LMNAEGLN1ALKBH5SUCNR1ALDH1A1 | |
| Succinic Acid SCHEMBL2967165 | 0.89 | LMNA (0.45) | LMNAEGLN1ALKBH5SUCNR1ALDH1A1 | |
| Glutarate SCHEMBL22490703 | 0.88 | SLC22A6 (0.61) | LMNAEGLN1ALKBH5SUCNR1ALDH1A1 | |
| Glycerin SCHEMBL3469284 | 0.88 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1ALDH1A1 | |
| Adipic Acid SCHEMBL28688445 | 0.88 | LMNA (0.61) | LMNAALDH1A1SLC22A6CAMK2ATSHR | |
| Adipic Acid SCHEMBL270756 | 0.88 | LMNA (0.61) | LMNAALDH1A1SLC22A6CAMK2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113825485-B | Improved quick-break water-in-oil emulsions | 拜尔斯道夫股份有限公司 | 2023-11-28 | — | — | CN | claimed |
| CN-114269816-A | Porous cellulose microparticles and method for producing same | 阿诺米拉公司 | 2022-04-01 | — | — | CN | claimed |
| CN-113980252-A | Continuous production method of modified poly (butylene succinate) | 上海师范大学 | 2022-01-28 | — | — | CN | claimed |
| US-6793929-B2 | OIL PHASE CHOSEN FROM LIPIDS OR LIPID MIXTURES, INTERFACE-ACTIVE SUBSTANCE CHOSEN FROM ALKYLMETHICONE COPOLYOLS AND/OR ALKYLDIMETHICONE COPOLYOLS, CATIONIC POLYMERS | BEIERSDORF AG (DE) | 2004-09-21 | — | — | US | claimed |
| US-20030017176-A1 | Preparations of the W/O emulsion type with an increased water content, comprising moderately polar lipids and silicone emulsifiers and, if desired, cationic polymers | BEIERSDORF AG (DE) | 2003-01-23 | — | — | US | claimed |
| CN-119138471-A | Coffee milk and preparation method thereof | 内蒙古伊利实业集团股份有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-113784722-B | Formulations for oral delivery of poorly permeable proteins, peptides and small molecules | R·P·舍勒科技有限责任公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118812978-A | Biodegradable polyvinyl alcohol film for normal temperature hydrolytic cement package | 常州纺织服装职业技术学院 | 2024-10-22 | — | — | CN | disclosed |
| CN-113825485-B | Improved quick-break water-in-oil emulsions | 拜尔斯道夫股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-116113617-A | Process for preparing polyoxybutoxide esterified polyglyceryl polycarboxylic acid esters | IOI油脂化学品有限责任公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-115558044-A | Crosslinkable polymer emulsifier and preparation method thereof, latex matrix and emulsion explosive | 北矿亿博(沧州)科技有限责任公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-111093598-B | Oil-in-water emulsion compositions comprising ether oils | 莱雅公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-114269816-A | Porous cellulose microparticles and method for producing same | 阿诺米拉公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114144161-A | Oil-in-water sunscreen compositions | 拜尔斯道夫股份有限公司 | 2022-03-04 | — | — | CN | disclosed |