Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 7/20 | 0.41 |
| ▸ | CNR2 | P34972 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194863 | 0.99 | ALOX5 (0.50) | ALOX5THRATHRBCNR1CNR2 | |
| SCHEMBL7198457 | 0.97 | ALOX5 (0.47) | ALOX5THRATHRBCNR1CNR2 | |
| SCHEMBL7190360 | 0.93 | ALOX5 (0.43) | ALOX5THRATHRB | |
| SCHEMBL7198353 | 0.89 | THRA (0.47) | ALOX5THRATHRBCNR1CNR2 | |
| SCHEMBL7191740 | 0.89 | ALOX5 (0.49) | ALOX5THRATHRBCNR1CNR2 | |
| SCHEMBL7194122 | 0.88 | THRA (0.49) | ALOX5THRATHRBCNR1CNR2 | |
| SCHEMBL7194517 | 0.88 | THRA (0.51) | ALOX5THRATHRBCNR1CNR2 | |
| SCHEMBL7188363 | 0.88 | ALOX5 (0.50) | ALOX5THRATHRBCNR1CNR2 | |
| SCHEMBL7193858 | 0.87 | THRA (0.53) | ALOX5THRATHRBCNR1CNR2 | |
| SCHEMBL7198468 | 0.86 | THRB (0.48) | ALOX5THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | STATENS SERUM INSTITUTE (DK) | 2003-04-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | AKR1C3, AKR1C1, AKR1A1 | ALOX5 1298/4885THRA 2660/4885THRB 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.