Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6095015 | 0.83 | LMNA (0.39) | ADORA2AADORA1LMNAALDH1A1MAPT | |
| SCHEMBL6094959 | 0.75 | KCNE1 (0.51) | ERCC1FEN1ERCC4MEN1KMT2A | |
| SCHEMBL6092877 | 0.73 | CNR1 (0.46) | — | |
| SCHEMBL6093853 | 0.72 | MMP13 (0.47) | MEN1KMT2A | |
| SCHEMBL6883899 | 0.66 | MEN1 (0.44) | MEN1PABPC1KMT2AADORA2AADORA1 | |
| SCHEMBL18832230 | 0.64 | ERCC1 (0.36) | ERCC1FEN1ERCC4LMNAALDH1A1 | |
| SCHEMBL27803655 | 0.62 | ALDH1A1 (0.43) | LMNAALDH1A1MAPT | |
| SCHEMBL30621294 | 0.60 | KDM4E (0.61) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL17825684 | 0.60 | NPC1 (0.44) | ADORA2AADORA1LMNAALDH1A1MAPT | |
| SCHEMBL5766494 | 0.60 | KMT2A (0.40) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004062613-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-07-29 | — | — | WO | disclosed |