Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873942 | 0.88 | LMNA (0.36) | HDAC9LMNAMMEMMP8OPRM1 | |
| SCHEMBL6263927 | 0.84 | MAPT (0.35) | LMNATSHROPRM1OPRD1OPRK1 | |
| SCHEMBL18091534 | 0.82 | ESR2 (0.35) | HDAC9MMEMMP8 | |
| SCHEMBL24483673 | 0.81 | CHRM3 (0.36) | LMNAMMETSHROPRM1OPRD1 | |
| SCHEMBL20130556 | 0.80 | HTR2A (0.42) | HDAC9OPRM1OPRD1OPRK1 | |
| SCHEMBL28209603 | 0.80 | HDAC9 (0.33) | HDAC9MMETSHRMMP8OPRM1 | |
| SCHEMBL14659945 | 0.78 | ADRA1D (0.38) | HDAC9MMEOPRM1 | |
| SCHEMBL27499227 | 0.78 | ADRA2A (0.40) | LMNATSHROPRM1OPRD1OPRK1 | |
| SCHEMBL6882704 | 0.75 | SIGMAR1 (0.37) | LMNATSHR | |
| SCHEMBL6882706 | 0.75 | SIGMAR1 (0.37) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1059299-B1 | Process for the polymerisation of olefins in the presence of indenyl compounds | SABIC POLYPROPYLENES BV (NL) | 2003-12-17 | — | — | EP | disclosed |
| US-6342622-B1 | COMPOUNDS HAVING BRIDGING GROUP CONTAINING AT LEAST ONE SP2-HYBRIDISED CARBON ATOM BONDED TO INDENYL GROUP AT 2-POSITION ARE MORE ACTIVE AND/OR GIVE POLYMERS WITH HIGHER MOLECULAR WEIGHT | DSM B.V. (NL) | 2002-01-29 | — | — | US | disclosed |
| EP-1059299-A1 | Indenyl compounds for the polymerisation of olefins | DSM N.V. (NL) | 2000-12-13 | — | — | EP | disclosed |
| EP-1059300-A1 | Indenyl compounds for the polymerisation of olefins | DSM N.V. (NL) | 2000-12-13 | — | — | EP | disclosed |